针刀疗法治疗膝骨关节炎的作用机制及研究进展  

Action mechanism and research progress of acupotomy therapy in the treatment of knee osteoarthritis

作　　者：李盈宏 王雅慧 姜益常[2] 刘家兴 蔡金广 LI Yinghong;WANG Yahui;JIANG Yichang;LIU Jiaxing;CAI Jinguang(Graduate School,Heilongjiang University of Chinese Medicine,Harbin,Heilongjiang 150040,P.R.China;Department of Orthopedics and Traumatology,the First Affiliated Hospital of Heilongjiang University of Chinese Medicine,Harbin,Heilongjiang 150040,P.R.China)

机构地区：[1]黑龙江中医药大学研究生院,哈尔滨150040 [2]黑龙江中医药大学附属第一医院骨伤三科,哈尔滨150040

出　　处：《华西医学》2025年第4期665-670,共6页West China Medical Journal

基　　金：黑龙江省科学技术厅黑龙江省自然科学基金项目(YQ2020H028);黑龙江省中医药管理局黑龙江省中医药科研项目(ZHY2023-220);第七批全国名老中医药专家学术经验继承项目(国中医药人教函【2022】76号)。

摘　　要：膝骨关节炎(knee osteoarthritis,KOA)是一种常见的慢性退行性骨关节疾病,尤其在中老年人群中发病率极高。KOA患者通常伴有关节疼痛和运动障碍,且该病具有一定的致残性,严重影响其生活质量。针刀疗法作为中医特色治疗手段之一,已被证明可减轻KOA患者的疼痛情况,并能有效延缓病情的快速恶化。因此,该文通过综述KOA的致病因素,并从力学结构、炎性因子水平、软骨修复情况及细胞自噬和凋亡角度探讨针刀疗法治疗KOA的作用机制,为针刀疗法在KOA临床实践中的应用提供更坚实的理论依据和治疗策略。Knee osteoarthritis(KOA)is a common chronic degenerative osteoarthritic disease with a high incidence especially among middle-aged and elderly people,and patients with KOA usually suffer from joint pain and dyskinesia,which is disabling and seriously affects their quality of life.Acupotomy therapy,as one of the characteristic treatments of traditional Chinese medicine,has been proven to significantly reduce the pain of KOA patients and effectively slow down the rapid deterioration of the disease.Therefore,this article reviews the pathogenic factors of KOA and explores the mechanism of action of acupotomy therapy for KOA from the perspectives of mechanical structure,level of inflammatory factors,cartilage repair,and cellular autophagy and apoptosis,in order to provide a more solid theoretical basis and therapeutic strategy for the application of acupotomy therapy in the clinical practice of KOA.

关 键 词：膝骨关节炎 针刀 致病因素 作用机制 

分 类 号：R246.9[医药卫生—针灸推拿学]