2018—2023年北京市大兴区发热呼吸道症候群监测病例中12种病原体的流行特征分析  

Analysis of 12 Pathogens in surveillance cases of febrile respiratory syndrome in Daxing district of Beijing City from 2018 to 2023

作　　者：唐金凤[1] 雷红 刘美辰 李秋玲 李甜 王希峰[1] 甘亚弟[1] 张代涛[2] Tang Jinfeng;Lei Hong;Liu Meichen;Li Qiuling;Li Tian;Wang Xifeng;Gan Yadi;Zhang Daitao(Daxing Center for Disease Control and Prevention,Beijing 102600,China;Beijing Center for Disease Control and Prevention,Beijing 100013,China)

机构地区：[1]北京市大兴区疾病预防控制中心,北京102600 [2]北京市疾病预防控制中心,北京100013

出　　处：《中华预防医学杂志》2025年第4期478-483,共6页Chinese Journal of Preventive Medicine

摘　　要：2018—2023年北京市大兴区1557例发热呼吸道症候群(FRS)监测病例中,12种呼吸道病原体[人流感病毒(HIFV)、人呼吸道合胞病毒(HRSV)、人副流感病毒(HPIV)、人鼻病毒(HRV)、人肠道病毒(HEV)、人腺病毒(HadV)、人偏肺病毒(HMPV)、人博卡病毒(HBoV)、肺炎支原体(MP)、肺炎衣原体(CP)、人冠状病毒(HCoV)和新冠病毒(SARS-CoV-2)]的任一病原体检出率为25.31%(394/1557);检出率从高到低依次为HIFV、SARS-CoV-2、HRV、HPIV、MP、HCoV、HRSV、HEV、HMPV、HadV、HBoV、CP。2018—2019、2020—2022、2023年任一病原体检出率分别为26.98%(150/556)、15.81%(95/601)、37.25%(149/400),差异有统计学意义(χ^(2)=59.703,P<0.001)。与2018—2019年相比,2023年HIFV、HMPV检出率增加,HRV、MP、HEV、HBoV检出率下降,差异均有统计学意义(均P<0.05)。<15岁人群任一病原体检出居前3位的是HIFV、HRSV和HadV;≥60岁人群检出率居前3的是SARS-CoV-2、HIFV和HRV。A total of 1557 cases were included in the Febrile Respiratory Syndrome(FRS)surveillance conducted in Daxing District between 2018 and 2023.Twelve respiratory pathogens were investigated:human influenza virus(HIFV),human respiratory syncytial virus(HRSV),human parainfluenza virus(HPIV),human rhinovirus(HRV),human enterovirus(HEV),human adenovirus(HadV),human metapneumovirus(HMPV),human bocavirus(HBoV),Mycoplasma pneumoniae(MP),Chlamydia pneumoniae(CP),human coronavirus(HCoV),and severe acute respiratory syndrome coronavirus 2(SARS-CoV-2).Results demonstrated an overall pathogen detection rate of 25.31%(394/1557),with descending prevalence as follows:HIFV,SARS-CoV-2,HRV,HPIV,MP,HCoV,HRSV,HEV,HMPV,HadV,HBoV,and CP.Temporal analysis revealed detection rates of 26.98%(150/556)for 2018-2019,15.81%(95/601)for 2020-2022,and 37.25%(149/400)for 2023,showing statistically significant interannual variation(χ^(2)=59.703,P<0.001).Compared with 2018-2019,2023 exhibited significantly elevated detection rates for HIFV and HMPV(P<0.05),while HRV,MP,HEV,and HBoV demonstrated significantly reduced rates(P<0.05).Age-stratified analysis identified HIFV,HRSV,and HadV as the predominant pathogens in individuals aged<15 years,whereas SARS-CoV-2,HIFV,and HRV predominated in those aged≥60 years.

关 键 词：发热呼吸道症候群 病原学 监测 

分 类 号：R725.6[医药卫生—儿科]