尿源性脓毒症早期预警指标研究进展  

Research progress on early warning indicators for urosepsis

作　　者：常阳 郑鑫[1] 施鸿金 王海峰 邰文琳[1] 李劲榆[1] CHANG Yang;ZHENG Xin;SHI Hongjin;WANG Haifeng;TAI Wenlin;LI Jinyu(Department of Clinical Labroratory,the Second Affiliated Hospital of Kunming Medical University,Kunming 650101,China;Department of Urology,the Second Affiliated Hospital of Kunming Medical University,Kunming 650101,China)

机构地区：[1]昆明医科大学第二附属医院检验科,云南昆明650101 [2]昆明医科大学第二附属医院泌尿外科,云南昆明650101

出　　处：《陕西医学杂志》2025年第5期707-710,共4页Shaanxi Medical Journal

基　　金：国家自然科学基金资助项目(82260609)。

摘　　要：尿源性脓毒症是一种由泌尿系统感染引起的脓毒血症,是泌尿外科和重症监护室常见的危重疾病之一,具有死亡率高和病情进展迅速的特点,若诊治不及时,可发展为脓毒性休克,导致患者多器官功能衰竭甚至死亡。尽管早期干预对改善患者预后至关重要,但目前仍缺乏特异性和敏感性较高的诊断标准。近年来,新兴的生物标志物在尿源性脓毒症的早期识别中展现出巨大潜力。现对尿源性脓毒症相关的早期预警生物标志物及其诊断性能和临床价值进行综述,为尿源性脓毒症的早期诊断提供新的视角与策略。Urosepsis,a type of sepsis caused by urinary tract infections,is a common critical illness in urology and intensive care units,characterized by high mortality and rapid disease progression.If not diagnosed and treated promptly,it can progress to septic shock,leading to multiple organ dysfunction syndrome and even death.Despite the importance of early intervention in improving patient outcomes,current diagnostic criteria lack sufficient specificity and sensitivity.In recent years,emerging biomarkers have shown great potential in the early identification of urosepsis.This article reviews the early warning biomarkers related to urosepsis,their diagnostic performance,and clinical value,aiming to provide new perspectives and strategies for the early diagnosis of urosepsis.

关 键 词：尿源性脓毒症 早期预警 生物标志物 全身炎症反应综合征 早期诊断 

分 类 号：R631[医药卫生—外科学]