糖尿病精细分型的研究进展  

Advances in the fine classification of diabetes

作　　者：米稼钰 胡静涵 郭妍 MI Jiayu;HU Jinghan;GUO Yan(Student Team,College of Basic Medical Sciences,Naval Medical University(Second Military Medical University),Shanghai 200433,China;不详)

机构地区：[1]海军军医大学(第二军医大学)基础医学院学员队,上海200433 [2]海军军医大学第一附属医院内分泌科,上海200433

出　　处：《中国临床研究》2025年第4期623-628,共6页Chinese Journal of Clinical Research

基　　金：上海市自然科学基金面上项目(20ZR1456600)。

摘　　要：我国目前采用的糖尿病分型方案基于WHO(1999年版)的病因学分类体系,将糖尿病分为1型、2型、其他特殊类型和妊娠期糖尿病。然而,当前各种类型临床表现与诊断指标存在一定局限性,导致分型界限不清,并随着病情发展,分型可能转变为另一种。此外,不同类型的糖尿病需要采取不同治疗方案并且预后不同,因此准确的分型对于诊断和精准医学的实施至关重要。近来国际上越来越关注糖尿病的精细分型,以2022年《糖尿病分型诊断中国专家共识》为代表更新了对于糖尿病分型的建议,诸多研究对于糖尿病分型进行了更加细致全面地探索,涉及的生物标志物也越来越多。因此,本文拟对国内外有关糖尿病的新兴分型做一回顾和总结。The current diabetes classification in China is still based on the etiological classification system of the WHO(1999 edition),which divides diabetes into type 1,type 2,other specific types,and gestational diabetes.However,the clinical characteristics and diagnostic indicators for various types have certain limitations,leading to blurred boundaries between different classifications,As clinical indicators change,patients may transition from one type to another during disease progression.Furthermore,dfferent types of diabetes require different treatment strategies and have distinct prognoses,making accurate classification crucial for diagnosis and the implementation of precision medicine.Recently,there has been growing international attention on the fine classification of diabetes.The“2022 Chinese Expert Consensus on Diabetes Classification and Diagnosis”represents an updated requirement for diabetes classification.Many studies have explored diabetes classification in more detailed and comprehensive ways,with an increasing number of biomarkers involved in the classification.Therefore,this paper aims to review and summarize the emerging classifications both domestically and internationally.

关 键 词：糖尿病 精细分型 胰岛素依赖 继发性糖尿病 

分 类 号：R587[医药卫生—内分泌]