血液肿瘤患者经济毒性现状及影响因素的研究  

Study of current situations of economic toxicity and associated factors in hematological malignancies patients

作　　者：李金连 黄雅平 吴子瑾 田玲玲 岑楚娉 黄珊[1] LI Jinlian;HUANG Yaping;WU Zijin;TIAN Lingling;CEN Chupin;HUANG Shan(Department of Hematology,Sun Yat-sen Memorial Hospital,Sun Yat-sen University,Guangzhou 520120,Guangdong,China)

机构地区：[1]中山大学孙逸仙纪念医院血液内科,广东广州520120

出　　处：《中国现代医生》2025年第11期35-38,共4页China Modern Doctor

摘　　要：目的 了解血液肿瘤患者的经济毒性现状并分析其与生活质量、心理韧性的相关性。方法 选取2022年12月至2023年10月中山大学孙逸仙纪念医院收治的135例血液肿瘤患者作为研究对象。采用一般资料调查表、经济毒性综合评分量表、生活质量核心量表、心理韧性量表社会支持评定量表进行调查。采用Pearson法进行相关分析,控制混杂因素后采用多重线性回归分析经济毒性的影响因素。结果 患者经济毒性得分为(15.95±0.84)分,其中82.2%血液肿瘤患者存在经济毒性。与功能型生活质量(r=0.464,P<0.001)及心理韧性(r=0.232,P=0.007)呈正相关,与症状型心理质量呈负相关(r=-0.440,P<0.001);多重线性回归分析结果显示,血液肿瘤经济毒性的影响因素为生活质量、对治疗费用的了解、治疗疗程、患者性格,无第二照顾者(P<0.05)。结论 血液肿瘤患者的经济毒性水平较高,可影响其生活质量及心理韧性。Objective To investigate the current situations of economic toxicity in hematological malignancies patients,and explore it’s correlation with quality of life and psychological resilience.Methods A total of 135 hematological malignancies patients admitted in Sun Yat-sen Memorial Hospital,Sun Yat-sen University from December 2022 to October 2023 were selected as subjects.Patients were surveyed by using general information and disease-related information questionnaires,comprehensive scores for financial toxicity,European organization for research and treatment of cancer core questionnaire,connor-davidson resilience scale,social support rating sale.Correlation analysis was performed by using the Pearson method.Multiple linear regression was used to analyze the factors of economic toxicity after controlling for confounding factors.Results Economic toxicity score of 135 hematological malignancies patients was(15.95±0.84)points,of which 82.2%of them had economic toxicity.It was positively correlated with functional quality of life(r=0.464,P=<0.001)and psychological resilience(r=0.232,P=0.007),and negatively correlated with symptomatic psychological quality(r=-0.440,P<0.001).Multiple linear regression analysis showed that quality of life,knowledge of the treatment cost,course of treatment,patient personality and have no second caregiver were influencing factors of economic toxicity of hematological malignancies(P<0.05).Conclusion Hematological malignancies patients have a higher level of economic toxicity,which can affect their quality of life and psychological resilience.

关 键 词：血液肿瘤 经济毒性 生活质量 社会支持 

分 类 号：R473.5[医药卫生—护理学]