射频消融与微波消融治疗钙化性甲状腺结节的临床效果对比研究  

Radiofrequency ablation and the clinical effect of microwave ablation in treatment of calcified thyroid nodule

作　　者：景娜[1] 郭亮[1] Jing Na;Guo Liang(Department of General Thoracic Tumor Surgery,Xi′an Electric Power Central Hospital,Shaanxi 710043,China)

机构地区：[1]西安电力中心医院普胸肿瘤外科,710043

出　　处：《山西医药杂志》2025年第8期576-580,共5页Shanxi Medical Journal

摘　　要：目的对比分析射频消融(RFA)与微波消融(MWA)在治疗钙化性甲状腺结节中的疗效。方法回顾性分析2022年3月至2024年3月在我院接受治疗的84例钙化性甲状腺结节患者的临床资料。根据治疗方式将患者分为RFA组42例和MWA组42例。比较2组患者在治疗前、治疗后1个月、3个月、6个月的结节体积缩减率(VRR)、甲状腺功能指标、手术时间、并发症发生率及患者瘢痕恢复效果等指标。结果治疗后6个月,RFA组VRR为(85±7)%,高于MWA组的(76±8)%(P<0.05)。RFA组手术时间[(15±3)min]短于MWA组(21±4)min。2组患者在治疗后甲状腺功能均保持在正常范围内,且组间差异无统计学意义(P>0.05)。并发症方面,RFA组发生率(5%)低于MWA组(12%)(P<0.05),RFA组患者术后1个月的患者评价量表(PSAS)、观察者评价量表(OSAS)评分均优于MWA组(P<0.05),术后3个月和6个月的PSAS、OSAS评分比较差异无统计学意义(P>0.05)。结论与微波消融相比,射频消融在治疗钙化性甲状腺结节方面具有更高的体积缩减率、更短的手术时间、更低的并发症发生率和更好的瘢痕恢复效果,是一种安全有效的治疗方案。Objective To analyze the curative effect of radiofrequency ablation(RFA)and microwave ablation(MWA)in the treatment of calcification in thyroid nodules.Methods The clinical data of 84 patients with calcified thyroid nodules treated in our hospital from March 2022 to March 2024 were retrospectively analyzed.The patients were divided into the RFA group(42 cases)and the MWA group(42 cases).The volume reduction ratio(VRR)of nodules before treatment,1 month,3 months and 6 months after treatment was compared between the two groups,thyroid function[thyroid stimulating hormone(TSH),free triiodothyronine(FT3),free thyroxine(FT4)],operative time,complication rate and scar recovery effect of patients were compared.Results Six months after treatment,VRR in the RFA group was(85±7)%,which was higher than that in the MWA group(76±8)%(P<0.05).The procedure time was less in the RFA group than in the MWA group[(15±3)min vs(21±4)min].The thyroid function of the two groups remained within the normal range after treatment,and there was no statistical significance between the two groups(P>0.05).In terms of complications,the incidence rate of the RFA group(5%)was lower than that of the MWA group(12%)(P<0.05),and the scores of psychosocial stress rating scale(PSAS)and OSAS in the RFA group were better than those in the MWA group one month after surgery(P<0.05).There was no significant difference in PSAS and OSAS scores between 3 and 6 months after operation(P>0.05).Conclusion Radiofrequency ablation compared with microwave ablation,has a higher volume reduction rate,shorter operation time,fewer complications and better effect of scar recovery,which is a kind of safe and effective treatment.

关 键 词：甲状腺结节 体积描记术 射频消融术 微波 

分 类 号：R581[医药卫生—内分泌]