微聚焦超声联合窄谱强脉冲光治疗面部皮肤老化的效果及安全性  

Efficacy and safety of focused ultrasound combined with dye pulsed light for treatment of facial skin aging

作　　者：倪智敏 戚世玲 徐书伟[3] 颜海燕 Ni Zhimin;Qi Shilong;Xu Shuwei;Yan Haiyan(Zhiyan Medical Beauty Clinic,Guangzhou 510620,China;Department of Dermatology,the Fifth Affiliated Hospital of Guangzhou Medical University,Guangzhou 510700,China;Department of Rehabilitation,Sun Yat-sen Memorial Hospital of Sun Yat-sen University,Guangzhou 510120,China)

机构地区：[1]智颜医疗美容诊所,广州510620 [2]广州医科大学附属第五医院皮肤科,广州510700 [3]中山大学孙逸仙纪念医院康复科,广州510120

出　　处：《中华医学美学美容杂志》2025年第2期172-174,共3页Chinese Journal of Medical Aesthetics and Cosmetology

摘　　要：目的观察微聚焦超声(MFU)联合窄谱强脉冲光(DPL)治疗面部皮肤老化的效果及安全性。方法回顾性纳入智颜医疗美容诊所、广州医科大学附属第五医院、中山大学孙逸仙纪念医院2023年5至9月因面部皮肤老化接受治疗的患者133例,其中男46例,女87例,年龄24~45(34.5±3.7)岁。根据患者接受的治疗方式分为2组:联合治疗组55例,接受MFU联合DPL治疗;对照组77例,仅接受MFU治疗。所有患者治疗完成后,由3位临床医师对治疗前及治疗后即刻的照片进行疗效评估,包括改善、恶化、无效。比较两组患者疼痛程度评分以及皮肤反应评分。记录不良反应发生情况。结果所有患者治疗后的疗效改善率为100%(133/133)。联合治疗组疼痛评分为0.10(0.05,0.20)分,对照组为0.75(0.60,0.90)分,差异有统计学意义(Z=-6.66,P<0.001)。联合治疗组皮肤反应评分为0.40(0.20,0.60)分,对照组为1.20(0.90,1.50)分,差异有统计学意义(Z=-5.18,P<0.001)。所有患者治疗过程中均无治疗部位伤口及其他严重不良反应出现。结论MFU联合DPL治疗面部皮肤老化效果较好,无严重不良反应。Objective To observe the efficacy and safety of micro-focusing ultrasound(MFU)combined with dye pulsed light(DPL)in the treatment of facial skin aging.Methods A retrospective study was conducted in 133 patients treated for facial skin aging at Zhiyan Medical Beauty Clinic,the Fifth Affiliated Hospital of Guangzhou Medical University,and Sun Yat-sen Memorial Hospital of Sun Yat-sen University from May to September 2023.There were 46 males and 87 females,aged 24-45(34.5±3.7)years.Patients were divided into two groups based on the treatment they received:combined treatment group:55 cases,treated with MFU combined with DPL;control group:77 cases,treated with MFU only.After the completion of treatment in all patients,three clinical physicians evaluated the pre-treatment and immediate post-treatment photos for efficacy,including improvement,deterioration,and ineffectiveness.The pain degree scores and skin reaction scores were compared between the two groups.The occurrence of adverse reactions was recorded.Results After treatment,the improvement rate of all patients was 100%(133/133).The pain score of the combined treatment group was 0.10(0.05,0.20)points,and that of the control group was 0.75(0.60,0.90)points.The difference was statistically significant between the two groups(Z=-6.66,P<0.001).The skin reaction score of the combined treatment group was 0.40(0.20,0.60)points,and that of the control group was 1.20(0.90,1.50)points.The difference was statistically significant between the two groups(Z=-5.18,P<0.001).There were no treatment site wounds and other serious adverse reactions during the treatment of all patients.Conclusion MFU combined with DPL is effective in the treatment of facial skin aging without serious adverse reactions.

关 键 词：皮肤老化 强脉冲光 聚焦超声 

分 类 号：R751[医药卫生—皮肤病学与性病学]