心脏术后行连续性肾脏替代治疗患者死亡影响因素分析  

Analysis of influencing factors of death in patients undergoing continuous renal replacement therapy after cardiac surgery

作　　者：陈娟 赵君花 CHEN Juan;ZHAO Junhua(Hemodialysis Room,Changhai Affiliated Hospital of Naval Medical University,Shanghai 200433,China)

机构地区：[1]海军军医大学附属长海医院血透室,上海200433

出　　处：《中国医药科学》2025年第7期101-104,165,共5页China Medicine And Pharmacy

摘　　要：目的探讨心脏术后行连续性肾脏替代治疗(CRRT)患者死亡的影响因素。方法选择2021年1月至2023年7月在海军军医大学第一附属医院心血管外科术后接受CRRT的180例患者为研究对象,根据术后90 d死亡情况分为死亡组和存活组。采用单因素方差分析和二元logistic回归分析筛选心脏术后行CRRT患者死亡的影响因素。结果纳入180例心脏术后行CRRT的患者90 d内病死92例,病死率为51.11%。二元logistic回归分析结果显示,年龄>65岁、术中输血量及CRRT后12 h高乳酸水平是导致心脏术后行CRRT患者病死的危险因素(OR>1.5,P<0.05)。结论心脏术后接受CRRT的患者病死率较高,年龄>65岁、术中输血量及CRRT后12 h高乳酸水平是导致心脏术后行CRRT患者死亡的危险因素,临床应警惕高危患者,及时采取有效的干预措施,以改善该类患者预后,降低患者病死率。Objective To explore the influencing factors of mortality in patients undergoing continuous renal replacement therapy(CRRT)after cardiac surgery.Methods A total of 180 patients who received CRRT after cardiac surgery in the Department of Cardiovascular Surgery of First Affiliated Hospital of Naval Medical University from January 2021 to July 2023 were selected as the study subjects.They were divided into death group and survival group according to the death situation 90 days after surgery.Single factor analysis of variance and binary Logistic regression analysis were used to screen the influencing factors of death in patients undergoing CRRT after cardiac surgery.Results Among the 180 patients who underwent CRRT after cardiac surgery,92 died within 90 days,with a mortality rate of 51.11%.The results of binary Logistic regression analysis showed that age>65 years,intraoperative blood transfusion volume,and high lactate levels 12 hours after CRRT were risk factors for mortality in patients undergoing CRRT after cardiac surgery(OR>1.5,P<0.05).Conclusion Patients undergoing CRRT after cardiac surgery have a higher mortality rate.Age>65 years,intraoperative blood transfusion volume,and high lactate levels 12 hours after CRRT are risk factors for mortality in patients undergoing CRRT after cardiac surgery.Clinically,high-risk patients should be vigilant and effective intervention measures should be taken in a timely manner to improve the prognosis of such patients and reduce patient mortality.

关 键 词：心脏术后 连续性肾脏替代治疗 病死 影响因素 

分 类 号：R692.5[医药卫生—泌尿科学]