2018-2023年某医院住院患儿EB病毒感染情况及流行病学分析  

Prevalence and Epidemiological Characteristics of EB Virus Infection in Hospitalized Children in a Hospital from 2018 to 2023

作　　者：郭君健 GUO Junjian(Department of Clinical Laboratory,Affiliated Renhe Hospital of China Three Gorges University,Yichang 443001,Hubei,China)

机构地区：[1]三峡大学附属仁和医院检验科,湖北宜昌443001

出　　处：《医学信息》2025年第9期74-77,共4页Journal of Medical Information

摘　　要：目的了解住院患儿EB病毒感染情况及流行病学特征,为临床对EB病毒感染的诊断和治疗工作提供科学依据。方法选取2018年1月-2023年12月在三峡大学附属仁和医院住院治疗的9960例患儿作为研究对象,采用ELISA检测EB病毒血清学抗体,分析患儿EB病毒感染情况及其疾病谱、临床症状和体征构成比。结果在9960份血液标本中,其中7083例(71.11%)抗体谱提示EB病毒感染,包括现症感染971例(9.75%)、亚急性感染1305例(13.10%)、既往感染4807例(48.26%);男性4720份标本,检出阳性例数3323例,女性5240份标本,检出阳性例数3760例,男、女阳性率分别为70.40%、71.76%;感染者年龄段中EB病毒阳性率最高的是3~6岁,在3150份血液标本中,检出EB病毒阳性例数2763例,阳性率为87.71%;971例现症感染患儿的疾病谱中,传染性单核细胞增多症患者357例,占比为36.77%;其次为急性支气管炎患儿244例,占比为25.13%;临床症状及体征构成比中,表现为发热的患儿最多(505例),占比为52.01%;其次为咳嗽咳痰的患儿(215例),占比为22.14%。结论住院患儿EB病毒感染率较高,EB病毒阳性检出率有年龄差异,现症感染以传染性单核细胞增多症患儿为主,临床症状及体征以发热较为多见,医院应根据流学病学特征制定相应预防措施。Objective To understand the prevalence and epidemiological characteristics of EB virus infection in hospitalized children,and to provide a scientific basis for clinical diagnosis and treatment of EB virus infection.Methods A total of 9960 children who were hospitalized in Affiliated Renhe Hospital of China Three Gorges University from January 2018 to December 2023 were selected as the research objects.ELISA was used to detect EB virus serological antibodies,and the EB virus infection,disease spectrum,clinical symptoms and signs were analyzed.Results Among the 9960 blood samples,7083(71.11%)samples of the antibody profiles indicated EB virus infection,including 971(9.75%)samples were current infections,1305(13.10%)samples were subacute infections,and 4807(48.26%)samples were previous infections.There were 3323 positive cases in 4720 male specimens and 3760 positive cases in 5240 female specimens.The positive rates of male and female were 70.40%and 71.76%,respectively.The highest positive rate of EB virus in the infected age group was 3-6 years old.Among 3150 blood samples,2763 cases of EB virus positive were detected,with a positive rate of 87.71%.In the disease spectrum of 971 children with current infection,there were 357 patients with infectious mononucleosis,accounting for 36.77%;followed by 244 cases of acute bronchitis,accounting for 25.13%;among the constituent ratio of clinical symptoms and signs,children with fever were the most(505 cases),accounting for 52.01%;followed by children with cough and expectoration(215 cases),accounting for 22.14%.Conclusion The infection rate of EB virus in hospitalized children is high,and the positive detection rate of EB virus has age difference.The current infection is mainly in children with infectious mononucleosis.The clinical symptoms and signs are more common in fever.The hospital should formulate corresponding preventive measures according to the characteristics of epidemiology.

关 键 词：EB病毒 住院患儿 流行病学 

分 类 号：R725.1[医药卫生—儿科]