支气管扩张剂治疗慢性阻塞性肺疾病的研究进展  

Research Progress on Bronchodilators in Treatment of Chronic Obstructive Pulmonary Disease

作　　者：沈铁涛 Shen Tietao(Department of Pharmacy,The Second Hospital of Lanzhou University,Lanzhou 730030,Gansu Province,China)

机构地区：[1]兰州大学第二医院药学部,甘肃兰州730030

出　　处：《中国社区医师》2025年第9期3-5,共3页Chinese Community Doctors

摘　　要：慢性阻塞性肺疾病患者气道狭窄或阻塞,呼吸时气流不通畅,常有咳嗽、咳痰、胸闷气喘等症状。临床上一般采用支气管扩张剂和抗炎药物治疗慢性阻塞性肺疾病。该文重点介绍了各类支气管扩张剂(抗胆碱能药物、β_(2)受体激动剂、甲基黄嘌呤类药物及新型磷酸二酯酶抑制剂)在慢性阻塞性肺疾病治疗中的应用情况,包括作用机制、具体疗效等,以期优化慢性阻塞性肺疾病的临床治疗方案。Patients with chronic obstructive pulmonary disease(COPD)experience airway stenosis or blockage,as well as airflow obstruction during breathing,and often have symptoms such as cough,sputum production,chest distress and asthma.In clinical practice,bronchodilators and anti-inflammatory drugs are generally used to treat chronic obstructive pulmonary disease.This article focuses on the application of various bronchodilators(anticholinergic drugs,β_(2)receptor agonists,methylxanthines and novel phosphodiesterase inhibitors)in the treatment of chronic obstructive pulmonary disease,including the mechanism of action and specific efficacy,so as to optimize the clinical treatment regimen of chronic obstructive pulmonary disease.

关 键 词：支气管扩张剂 用药不良反应 慢性阻塞性肺疾病 

分 类 号：R563[医药卫生—呼吸系统]