综合血液管理措施在成人二尖瓣手术中的应用效果  

Application effect of comprehensive blood management measures in adult mitral valve surgery

作　　者：郭建 路晓明 程思强[1] 崔金珍 GUO Jian;LU Xiaoming;CHENG Siqiang;CUI Jinzhen(Cardiac Vascular Surgery Department,the Second People's Hospital of Liaocheng,Linqing 252600,China;Gastroenterology Department,the Second People's Hospital of Liaocheng,Linqing 252600,China;No.3 Ward of Cardiology Department,the Second People's Hospital of Liaocheng,Linqing 252600,China)

机构地区：[1]聊城市第二人民医院心脏大血管外科,山东临清252600 [2]聊城市第二人民医院消化内科,山东临清252600 [3]聊城市第二人民医院心内科三病区,山东临清252600

出　　处：《临床医学研究与实践》2025年第12期70-73,共4页Clinical Research and Practice

摘　　要：目的探讨不同血液管理措施在成人二尖瓣手术中的应用效果及对术后输血量及术后转归的影响。方法选取在本院实施二尖瓣手术的70例成人患者进行回顾性分析,依据术中所使用的血液管理措施将其分为试验组(38例)和对照组(32例)。试验组实施综合血液管理措施,对照组未实施规范的血液管理措施。比较两组的术后48 h血红蛋白(Hb)水平、红细胞悬液输注量、血浆输注量、输注红细胞例数、输注血浆例数、自体血回输例数、住院时间、抗菌药物使用时间、抗菌药物使用种类。结果两组的术后48 h Hb水平比较,差异无统计学意义(P>0.05);试验组的红细胞悬液输注量和血浆输注量少于对照组,输注红细胞、输注血浆占比低于对照组,自体血回输占比高于对照组,差异具有统计学意义(P<0.05)。试验组的住院时间、抗菌药物使用时间短于对照组,使用1种抗菌药物占比高于对照组,差异具有统计学意义(P<0.05)。结论综合血液管理措施在成人二尖瓣手术中的效果明显,可减少围术期红细胞和血浆的输注量,且能在一定程度上缩短患者的住院时间和抗菌药物使用时间,值得临床推广。Objective To explore the application effect of different blood management measures in adult mitral valve surgery and its influences on postoperative blood transfusion volume and postoperative outcome.Methods A retrospective analysis was performed on 70 adult patients who underwent mitral valve surgery in our hospital.According to the blood management measures used during the operation,the patients were divided into experimental group(38 cases)and control group(32 cases).The experimental group implemented comprehensive blood management measures,while the control group did not implement standardized blood management measures.The hemoglobin(Hb)level at 48 h after operation,red blood cell suspension infusion volume,plasma infusion volume,number of red blood cell transfusion cases,number of plasma transfusion cases,number of autologous blood transfusion cases,hospitalization time,antibacterial drug use time and antibacterial drug use types were compared between the two groups.Results There was no significant difference in Hb level between the two groups at 48 h after operation(P>0.05);the amount of red blood cell suspension infusion and plasma infusion in the experimental group were less than those in the control group,the proportion of red blood cell transfusion and plasma transfusion were lower than those in the control group,and the proportion of autologous blood transfusion was higher than that in the control group,the differences were statistically significant(P<0.05).The hospitalization time and antibacterial drug use time of the experimental group were shorter than those of the control group,and the proportion of using one antibacterial drug was lower than that of the control group,the differences were statistically significant(P<0.05).Conclusion The comprehensive blood management measures in adult mitral valve surgery has a obvious effect,it can reduce the infusion of red blood cells and plasma during perioperative period,and can shorten the hospitalization time and antibiotic use time of patients to a certain

关 键 词：输血 节约用血 体外循环 心脏手术 二尖瓣 

分 类 号：R654.2[医药卫生—外科学]