猪肠道发育及其品种间差异的研究进展  

Research Progress of Pig Intestinal Development and Its Differences among Breeds

作　　者：谢启正 徐康[2] 王桂文 印遇龙[1,2] XIE Qizheng;XU Kang;WANG Guiwen;YIN Yulong(Key Laboratory of Livestock and Poultry Resources(Pig)Evaluation and Utilization,Ministry of Agriculture and Rural Affairs,College of Animal Science and Technology,Hunan Agricultural University,Changsha 410128,China;Key Laboratory of Animal Nutritional Physiology and Metabolic Process of Hunan,National Engineering Laboratory for Pollution Control and Resource Utilization Technology in Livestock and Poultry Breeding,Key Laboratory of Agro-Ecological Processes in Subtropical Region of Chinese Academy of Sciences,Institute of Subtropical Agriculture,Chinese Academy of Sciences,Changsha 410125,China;Ningxiang Animal Epidemic Disease Prevention Control Center,Ningxiang 410600,China)

机构地区：[1]湖南农业大学动物科学技术学院,农业农村部畜禽资源(猪)评价利用重点实验室,长沙410128 [2]中国科学院亚热带农业生态研究所,中国科学院亚热带农业生态过程重点实验室,畜禽养殖污染控制与资源化技术国家工程实验室,湖南省动物营养生理与代谢过程重点实验室,长沙410125 [3]宁乡市动物疫病预防控制中心,宁乡410600

出　　处：《动物营养学报》2025年第4期2119-2133,共15页CHINESE JOURNAL OF ANIMAL NUTRITION

基　　金：湖南省自然科学基金项目(2023JJ20043);中国科学院战略性先导科技专项(A类)(XDA24030204);国家自然科学基金项目(32372913);湖南省科技创新计划(2023RC3204)。

摘　　要：肠道是哺乳动物消化吸收的主要场所,其生理结构及功能复杂。肠道发育进程对肠道功能正常发挥至关重要。肠道发育从胚胎期开始,随着猪个体的生长发育,肠道形态和功能也随之发生改变,表现为肠腔不断生长扩大,肠绒毛数量的增多与形态发生变化,肠道细胞类型和功能的完善,以及肠道菌群的丰富等。因此,本文综述了猪不同发育时期肠道结构与功能的变化特征,同时论述了影响肠道发育相关的分子调控机制,最后比较了中国地方猪种与引进猪种的肠道发育特性,旨在揭示不同猪品种肠道发育的差异,为猪品种改良及不同品种的营养方案定制提供参考。The intestine is the main place for mammals to digest and absorb nutrients,and its physiological structure and function are complex.The process of intestinal development is very important for the normal functioning of intestinal function.Intestinal development starts from the embryonic stage,and with the growth and development of individual pigs,intestinal morphology and function also change,which is manifested by the continuous growth and expansion of intestinal lumen,the increase of intestinal villus number and morphological changes,the improvement of intestinal cell types and functions,and the enrichment of intestinal microflora.Therefore,this paper reviewed the changes in intestinal structure and function of pigs in different developmental stages,discussed the molecular regulatory mechanisms related to intestinal development,and finally compared the intestinal development characteristics of Chinese local pig breeds and imported pig breeds,aiming to reveal the differences in intestinal development of different pig breeds and provide references for the improvement of pig breeds and the customization of nutritional programs of different breeds.

关 键 词：猪 肠道发育 分子机制 品种差异 

分 类 号：S828[农业科学—畜牧学]