一种小型多频FOT呼吸阻抗测量系统的设计与实现  

Design and Implementation of a Small Multi-Frequency FOT Respiratory Impedance Measurement System

作　　者：兰鸿 王兴凡 罗翔 李曙 LAN Hong;WANG Xingfan;LUO Xiang;LI Shu(School of Communication and Electronic Engineering,Jishou University,Jishou 416000,Hunan China;School of Biomedical Engineering,Guangzhou Medical University,Guangzhou 511000,China)

机构地区：[1]吉首大学通信与电子工程学院,湖南吉首416000 [2]广州医科大学生物医学工程学院,广东广州511000

出　　处：《吉首大学学报(自然科学版)》2025年第2期31-38,共8页Journal of Jishou University(Natural Sciences Edition)

基　　金：湖南省自然科学基金资助项目(2022JJ30474)。

摘　　要：基于强迫振荡原理,设计了一种多频复合模式的小型强迫振荡呼吸阻抗测量系统.该系统将4个频率(5,10,15,20 Hz)的正弦信号叠加作为强迫振荡激励源,经过STM32F407处理器把叠加的激励源信号通过功率放大电路输出至扬声器,从而产生振荡气流作用于人体呼吸系统;通过流量传感器和压力传感器采集反馈的流量和压力信号,采用变分模态分解算法对信号进行处理,来有效提取纯净的强迫振荡信号.经气流阻力测量和成人呼吸阻抗重复性测量实验验证,该系统稳定可靠,能够准确测量4个典型频率下的人体呼吸阻抗参数,适用于临床呼吸系统疾病的早期检测与评估.Based on the forced oscillation principle,a small-scale forced oscillation pulmonary function measurement system with multi-frequency compound mode is designed.Sine signals of four different frequencies(5,10,15,20 Hz)are superimposed as forced oscillation excitation sources,and the superimposed excitation source signals are output to the loudspeaker through the power amplifier circuit by the STM32F407 processor,generating oscillating airflow to act on the human respiratory system.The flow and pressure signals collected by flow sensor and pressure sensor are processed by variational mode decomposition algorithm to extract pure forced oscillation signals effectively.The experimental verification of airflow resistance measurement and adult repeatability respiratory impedance measurement shows that the system is stable and reliable,and can accurately obtain human respiratory impedance parameters,which is suitable for early detection and evaluation of clinical respiratory diseases.

关 键 词：强迫振荡呼吸阻抗测量系统 STM32F407 变分模态分解 呼吸阻抗测量 

分 类 号：TH776[机械工程—仪器科学与技术] R-331[机械工程—精密仪器及机械]