中国维持性血液透析患者尿毒症性瘙痒患病率的Meta分析  

Meta-analysis of the Prevalence of Uremic Pruritus in Chinese Maintenance Hemodialysis Patients

作　　者：田海萍 乔婉婉 温贤秀[2] TIAN Haiping;QIAO Wanwan;WEN Xianxiu(School of Nursing,Chengdu University of Traditional Chinese Medicine,Chengdu 610075,China;Department of Nursing,Sichuan Provincial People's Hospital,Chengdu 610072,China)

机构地区：[1]成都中医药大学护理学院,四川成都610075 [2]四川省医学科学院·四川省人民医院护理部,四川成都610072

出　　处：《智慧健康》2025年第5期125-128,共4页Smart Healthcare

摘　　要：目的系统评价中国维持性血液透析患者尿毒症性瘙痒的患病率。方法检索PubMed、Embase等国内外数据库,搜集至2024年6月的相关文献。使用Stata 14.0软件进行Meta分析。结果纳入26篇横断面研究,总样本量为13446例。Meta分析显示,中国MHD患者UP患病率为56.6%(95%CI=47.9%~65.2%)。亚组分析显示,患病率随发表年份逐渐增加;使用透析症状指数量表(DSI)评估有皮肤干燥症的患病率更高(P<0.05)。结论中国MHD患者UP的总患病率较高,应重点关注我国MHD患者皮肤状况,及早干预。Objective Systematically evaluate the prevalence of uremic pruritus in Chinese maintenance hemodialysis patients.Methods The PubMed,Embase and other databases were searched for collecting relevant literature up to June 2024.Meta-analysis was performed using Stata 14.0 software.Results 26 cross-sectional studies were included,the results of Meta-analysis showed that the prevalence of UP in Chinese patients with MHD was 56.6% (95%CI=47.9%~65.2%).Subgroup analyses showed that the prevalence of UP in Chinese MHD patients increased progressively with the year of publication;the prevalence was higher in those assessed using the Dialysis Symptom Index Scale (DSI) and with dry skin syndrome (P<0.05).Conclusion The prevalence of UP in Chinese MHD patients is high.Focus should be placed on the skin condition of MHD patients in China for early intervention.

关 键 词：维持性血液透析 尿毒症性瘙痒 患病率 META分析 

分 类 号：R692.5[医药卫生—泌尿科学]