2017-2023年浙江省艾滋病监测哨点新型毒品使用者HIV抗体阳性及影响因素分析  

Analysis of HIV antibody positivity and influencing factors among new type drug users at AIDS surveillance posts in Zhejiang Province from 2017 to 2023

作　　者：袁柱 徐云[2] 程伟[2] 杨介者[2] 蒋均[2] 陈琳[2] 潘晓红[2,3] Yuan Zhu;Xu Yun;Cheng Wei;Yang Jiezhe;Jiang Jun;Chen Lin;Pan Xiaohong(School of Public Health,Health Science Center,Ningbo University,Ningbo 315211,China;Institute of AIDS/STD Prevention and Control,Zhejiang Provincial Center for Disease Control and Prevention,Hangzhou 310051,China;Zhejiang Association of STD/AIDS Prevention and Control,Hangzhou 310005,China)

机构地区：[1]宁波大学医学部公共卫生学院,宁波315211 [2]浙江省疾病预防控制中心艾滋病与性病预防控制所,杭州310051 [3]浙江省性病艾滋病防治协会,杭州310005

出　　处：《中华流行病学杂志》2025年第4期662-668,共7页Chinese Journal of Epidemiology

基　　金：国家科技重大专项(2017ZX10201101);浙江省疾病预防控制科技计划(2025JK166)。

摘　　要：目的分析浙江省2017-2023年艾滋病监测哨点新型毒品使用者HIV抗体阳性情况及影响因素。方法2017-2023年,浙江省吸毒人群的艾滋病监测哨点开展连续横断面调查,7个城市的9个吸毒人群监测哨点中,每个哨点样本量为400人。问卷调查其社会人口学信息、相关行为学信息、艾滋病知晓情况、干预措施接受情况,并采集血液进行HIV和梅毒抗体检测,以监测人群中新型毒品使用者为研究对象,应用SPSS 22.0软件进行统计学分析。结果共调查新型毒品使用者13955人,2017-2023年新型毒品使用者人数分别为2518、2292、2526、2119、2161、1064和1275人,HIV抗体阳性率分别为0.44%、1.09%、2.06%、1.09%、1.39%、1.50%、2.90%,HIV抗体阳性率和标准化HIV抗体阳性率呈上升趋势(均P<0.001),多因素logistic回归分析结果显示,婚姻状况为未婚/离异/丧偶(aOR=3.92,95%CI:2.46~6.25)、外省户籍(aOR=3.54,95%CI:2.34~5.35)、高中及以上文化程度(aOR=5.42,95%CI:3.68~7.98)、最近1年吸毒后发生性行为(aOR=1.84,95%CI:1.19~2.84)、知道使用新型毒品会增加HIV感染风险(aOR=2.27,95%CI:1.17~4.39)是新型毒品使用者HIV抗体阳性率升高的影响因素。结论2017-2023年浙江省新型毒品使用者HIV抗体阳性率呈上升趋势,需要加强对该人群的监测和干预。Objective To analyze the HIV antibody positivity of new type drug users in drug abuse monitoring sites in Zhejiang Province from 2017 to 2023 and its influencing factors.Methods From 2017 to 2023,a continuous cross-sectional survey was carried out in HIV monitoring posts among new type drug users in Zhejiang Province,the sample size was 400 people per site of 9 drug abuse surveillance sites in 7 cities.Questionnaires were conducted to investigate their social demographic information,related behavioral information,AIDS awareness,and acceptance of intervention measures,and blood was collected for HIV and syphilis antibody detection,with new type drugs users in the monitoring population as the research object.SPSS 22.0 software was used for statistical analysis.Results A total of 13955 new drug users were surveyed,and the number of new drug users was 2518,2292,2526,2119,2161,1064 and 1275 from 2017 to 2023,respectively,the HIV antibody positive rate of new type drugs users was 0.44%,1.09%,2.06%,1.09%,1.39%,1.50%,2.90%,respectively,and the HIV antibody positive standardized rate showed an increasing trend(all P<0.001).The results of multivariate logistic regression analysis showed that marital status:unmarried/divorced/widowed(aOR=3.92,95%CI:2.46-6.25),provincial household registration(aOR=3.54,95%CI:2.34-5.35),high school education or above(aOR=5.42,95%CI:3.68-7.98),sexual activity within the last 1 year after drug use(aOR=1.84,95%CI:1.19-2.84),and knowledge that the use of new drugs increases the risk of HIV infection(aOR=2.27,95%CI:1.17-4.39)were associated with increased HIV antibody favorable rates among new type drugs users.Conclusions During 2017-2023,the HIV antibody-positive rate of new type drug users in Zhejiang Province showed an upward trend.It is necessary to strengthen the monitoring and intervention of this population.

关 键 词：新型毒品 HIV抗体阳性 趋势 影响因素 

分 类 号：R512.91[医药卫生—内科学]