基于加权逼近理想解排序法建立儿童患者痰热清注射液的药物利用评价细则  

Drug Utilization Evaluation of Tanreqing Injection in Children Based on Weighted Technique for Order Preference by Similarity to Ideal Solution Method

作　　者：赵蕾 尚振海 赵兴辉 毛欣彤 韩兆欢 Zhao Lei;Shang Zhenhai;Zhao Xinghui;Mao Xintong;Han Zhaohuan(The Affiliated Hospital of Xuzhou Medical University,Jiangsu Xuzhou221006,China;The Affiliated Xuzhou Children’s Hospital of Xuzhou Medical University,Jiangsu Xuzhou221006,China)

机构地区：[1]徐州医科大学附属医院,江苏徐州221006 [2]徐州医科大学附属徐州儿童医院,江苏徐州221006

出　　处：《儿科药学杂志》2025年第5期18-21,共4页Journal of Pediatric Pharmacy

基　　金：江苏省药学会-奥赛康医院药学科研基金项目,编号A202339。

摘　　要：目的:建立基于加权逼近理想解排序(TOPSIS)法的儿童患者痰热清注射液的药物利用评价(DUE)细则,促进临床合理用药。方法:以痰热清注射液药品说明书为依据,参照痰热清注射液临床应用相关文献,建立基于加权TOPSIS法的儿童患者痰热清注射液的DUE标准,依据建立的DUE标准回顾性评价徐州医科大学附属徐州儿童医院2024年1-11月痰热清注射液应用情况。结果:200份病历应用加权TOPSIS法评价显示,相对接近程度(Ci)≥80%的有45例(22.50%),60%≤Ci<80%有128例(64.00%),Ci<60%有27例(13.50%)。不合理用药情况主要表现在用药疗程、实验室检查、给药剂量、潜在重复用药等方面。结论:基于加权TOPSIS法的儿童患者痰热清注射液DUE标准可用于儿童患者的用药合理性评价,评价结果显示我院痰热清注射液临床应用基本合理,仍存在部分不合理用药情况,需进一步加强管理从而促进其合理用药。Objective:To establish the drug utilization evaluation(DUE)of Tanreqing injection in children based on weighted technique for order preference by similarity to ideal solution(TOPSIS)method,and to promote the rational clinical application.Methods:The DUE criteria of Tanreqing injection in children based on weighted TOPSIS method was established with reference to drug instructions and relevant guidelines.The application of Tanreqing injection in the Affiliated Xuzhou Children’s Hospital of Xuzhou Medical University from Jan.to Nov.2024 were retrospectively evaluated according to the established DUE criteria.Results:The evaluation of 200 medical records by weighted TOPSIS method showed there were 45 cases(22.50%)with relative closeness coefficient(Ci)≥80%,128 cases(64.00%)with Ci≥60%and<80%,and 27 cases(13.50%)with Ci<60%.The irrational drug use was mainly manifested in the course of treatment,laboratory examination,dosage,and potential repeated medication.Conclusion:The DUE criteria of Tanreqing injection in children based on weighted TOPSIS method can be used to evaluate the application rationality of Tanreqing injection in children.The evaluation results show that the clinical application of Tanreqing injection in our hospital is basically rational,yet there are still irrational application of Tanreqing injection,which needs to be further strengthened.

关 键 词：儿童 加权逼近理想解排序法 痰热清注射液 药物利用评价 

分 类 号：R969.3[医药卫生—药理学]