运脾止泻方联合神阙灸治疗小儿泄泻脾虚证40例临床观察  

Clinical observation on the treatment of 40 cases of pediatric diarrhea of spleen deficiency type using Yunpi Zhixie Fang(运脾止泻方)combined with Shenque(RN8)moxibustion

作　　者：秦福海 白冬梅 于峰伟 QIN Fuhai;BAI Dongmei;YU Fengwei(First Pediatric Ward,Zhumadian Hospital of Traditional Chinese Medicine,Zhumadian,Henan,463000,China)

机构地区：[1]驻马店市中医院儿科一病区,河南驻马店463000

出　　处：《中医儿科杂志》2025年第2期51-55,共5页Journal of Pediatrics of Traditional Chinese Medicine

摘　　要：目的观察运脾止泻方联合神阙灸治疗小儿泄泻脾虚证的临床疗效。方法选取2021年3月至2023年3月驻马店市中医院儿科一病区门诊治疗的泄泻脾虚证患儿80例,按照随机数字表法分为对照组和治疗组,各40例。对照组予布拉氏酵母菌散、头孢克肟干混悬剂口服,并予补液盐以预防脱水和水电解质紊乱;治疗组予运脾止泻方结合神阙灸治疗。2组均治疗5 d后统计临床疗效。结果治疗组总有效率为97.50%(39/40),对照组为85.00%(34/40),2组比较,差异有统计学意义(P<0.05)。治疗前,2组主症、次症积分和总积分比较,差异无统计学意义(P>0.05),具有可比性;治疗后,2组主症、次症积分和总积分均显著下降,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组下降更显著(P<0.05)。治疗前,2组血清免疫球蛋白A(IgA)、免疫球蛋白G(IgG)、免疫球蛋白M(IgM)水平比较,差异无统计学意义(P>0.05),具有可比性;治疗后,2组血清IgA、IgG、IgM水平均显著升高,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组升高更显著(P<0.05)。治疗前,2组肠杆菌、肠球菌、双歧杆菌、乳酸杆菌数量比较,差异无统计学意义(P>0.05),具有可比性;治疗后,2组肠杆菌、肠球菌数量显著下降,双歧杆菌、乳酸杆菌数量显著升高,与同组治疗前比较,差异均有统计学意义(P<0.05),且治疗组下降或升高更显著(P<0.05)。结论运脾止泻方联合神阙灸治疗小儿泄泻脾虚证,能明显改善患儿的临床症状、体征,动态平衡肠道菌群,提高机体免疫力,效果显著,值得临床推广应用。Objective To observe the clinical efficacy of Yunpi Zhixie Fang(运脾止泻方)combined with Shenque(RN8)moxibustion in treating pediatric diarrhea of spleen deficiency type.Methods A total of 80children with diarrhea of spleen deficiency type treated at the outpatient clinic of the First Pediatric Ward,Zhumadian Hospital of Traditional Chinese Medicine,from March 2021 to March 2023 were selected and randomly divided into a control group and a treatment group,with 40 cases in each group.The control group was treated with Saccharomyces boulardii powder and cefixime dry suspension orally,along with oral rehydration salts to prevent dehydration and electrolyte imbalance.The treatment group was treated with Yunpi Zhixie Fang combined with Shenque(RN8)moxibustion.Clinical efficacy was evaluated after 5 days of treatment.Results The total effective rate in the treatment group was 97.50%(39/40),significantly higher than 85.00%(34/40)in the control group(P<0.05).Before treatment,there were no significant differences in the scores of primary symptoms,secondary symptoms,and total scores between the two groups(P>0.05),indicating comparability.After treatment,the scores of primary symptoms,secondary symptoms,and total scores decreased significantly in both groups compared to before treatment(P<0.05),with a more significant decrease in the treatment group(P<0.05).Before treatment,there were no significant differences in serum immunoglobulin A(Ig A),immunoglobulin G(Ig G),and immunoglobulin M(Ig M)levels between the two groups(P>0.05),indicating comparability.After treatment,serum Ig A,Ig G,and Ig M levels increased significantly in both groups compared to before treatment(P<0.05),with a more significant increase in the treatment group(P<0.05).Before treatment,there were no significant differences in the counts of Enterobacteria,Enterococci,Bifidobacteria,and Lactobacilli between the two groups(P>0.05),indicating comparability.After treatment,the counts of Enterobacteria and Enterococci decreased significantly,while the count

关 键 词：小儿泄泻 脾虚证 运脾止泻方 神阙灸 临床观察 

分 类 号：R256.34[医药卫生—中医内科学]