加味温胆汤联合耳穴压豆治疗儿童睡眠障碍痰热内扰型39例临床观察  

Clinical observation of modified Wendan Tang(加味温胆汤)combined with auricular acupressure in treating 39 cases of pediatric sleep disorder with phlegm-heat internal disturbance type

作　　者：郭丽娜 毕美芬 张雪锋 GUO Lina;BI Meifen;ZHANG Xuefeng(Department of Pediatrics,Zhenhai District Hospital of Traditional Chinese Medicine,Ningbo,Zhejiang,315200,China)

机构地区：[1]宁波市镇海区中医医院儿科,浙江宁波315200

出　　处：《中医儿科杂志》2025年第2期76-80,共5页Journal of Pediatrics of Traditional Chinese Medicine

基　　金：2023年宁波市镇海区公益性研究计划项目(202318)。

摘　　要：目的观察加味温胆汤联合耳穴压豆治疗儿童睡眠障碍痰热内扰型的临床疗效。方法选取2022年7月至2023年7月在宁波市镇海区中医医院儿科门诊治疗的睡眠障碍痰热内扰型患儿120例作为研究对象,按照随机数字表法分为对照组、中药组和联合组,各40例。治疗期间,对照组脱落3例,中药组脱落2例,联合组脱落1例,最终对照组37例,中药组38例,联合组39例。对照组口服葡萄糖酸钙口服溶液和维生素AD滴剂,中药组在对照组治疗方法的基础上予加味温胆汤治疗,联合组在中药组治疗方法的基础上加耳穴压豆治疗。3组均以1周为1个疗程,连续治疗4个疗程后统计临床疗效。结果联合组总有效率为97.44%(38/39),明显高于对照组的62.16%(23/37)和中药组的81.58%(31/38),3组组间比较,差异均有统计学意义(P<0.05)。治疗前,3组中医证候积分、匹兹堡睡眠质量指数量表(PSQI)评分比较,差异无统计学意义(P>0.05),具有可比性;治疗后,3组中医证候积分、PSQI评分均显著下降,与同组治疗前比较,差异均有统计学意义(P<0.05),且联合组下降更显著(P<0.05)。治疗前,3组血清白细胞介素-6(IL-6)、25-羟维生素D_(3)[25(OH)D_(3)]水平比较,差异无统计学意义(P>0.05),具有可比性;治疗后,中药组、联合组血清IL-6水平显著下降,与同组治疗前及对照组治疗后比较,差异均有统计学意义(P<0.05),且联合组下降更显著(P<0.05);对照组治疗前后血清IL-6水平比较,差异无统计学意义(P>0.05)。治疗后,3组25(OH)D_(3)水平均显著升高(P<0.05),且联合组升高更显著,与对照组与中药组比较,差异均有统计学意义(P<0.05)。治疗期间,对照组、中药组及联合组不良反应总发生率分别为10.81%(4/37)、10.52%(4/38)和12.81%(5/39),组间比较,差异均无统计学意义(P>0.05)。结论加味温胆汤联合耳穴压豆治疗儿童睡眠障碍痰热内扰型,能明显改善患儿的睡眠质量,疗效显著,且不�Objective To observe the clinical efficacy of Modified Wendan Tang(加味温胆汤)combined with auricular acupressure in treating pediatric sleep disorder of phlegm-heat internal disturbance type.MethodsA total of 120 children with sleep disorder of phlegm-heat internal disturbance type,treated in the outpatient department of pediatrics at Zhenhai District Hospital of Traditional Chinese Medicine from July 2022 to July 2023,were selected as the study subjects.They were randomly divided into a control group,a Chinese medicine group,and a combined group,with 40 cases in each group.During the treatment period,3 cases dropped out in the control group,2 in the Chinese medicine group,and 1 in the combined group.Ultimately,37 cases were included in the control group,38 in the Chinese medicine group,and 39 in the combined group.The control group was treated with oral calcium gluconate solution and vitamin AD drops.The Chinese medicine group received Modified Wendan Tang in addition to the control group's treatment.The combined group received auricular acupressure in addition to the Chinese medicine group's treatment.All three groups were treated for 4 weeks,with one week as one treatment course.Clinical efficacy was evaluated after 4 courses of treatment.ResultsThe total effective rate in the combined group was 97.44%(38/39),significantly higher than 62.16%(23/37)in the control group and 81.58%(31/38)in the Chinese medicine group.The differences among the three groups were statistically significant(P<0.05).Before treatment,there were no significant differences in TCM syndrome scores or Pittsburgh Sleep Quality Index(PSQI)scores among the three groups(P>0.05),indicating comparability.After treatment,TCM syndrome scores and PSQI scores in all three groups significantly decreased compared to pre-treatment(P<0.05),with the combined group showing a more pronounced decrease(P<0.05).Before treatment,there were no significant differences in serum interleukin-6(IL-6)and 25-hydroxy vitamin D_(3)[25(OH)D_(3)]levels among the three

关 键 词：睡眠障碍 儿童 痰热内扰型 加味温胆汤 耳穴压豆 临床观察 

分 类 号：R256.23[医药卫生—中医内科学]