穴位埋线辅助治疗儿童慢性持续期支气管哮喘肺肾气虚证42例临床观察  

Clinical observation on catgut embedding at acupoints as an adjuvant therapy for 42 cases of pediatric bronchial asthma in chronic persistent stage of lung-kidney qi deficiency type

作　　者：王艳鸽 刘书方 WANG Yange;LIU Shufang(Department of Traditional Chinese Medicine,Xuchang Central Hospital,Xuchang,Henan,461000,China;Department of Pediatrics,China-Japan Friendship Hospital,Beijing,100029,China)

机构地区：[1]许昌市中心医院中医内科,河南许昌461000 [2]中日友好医院儿科,北京100029

出　　处：《中医儿科杂志》2025年第2期81-85,共5页Journal of Pediatrics of Traditional Chinese Medicine

摘　　要：目的观察穴位埋线辅助治疗儿童慢性持续期支气管哮喘(BA)肺肾气虚证的临床疗效。方法选取2021年6月至2023年6月许昌市中心医院中医内科收治的84例慢性持续期BA肺肾气虚证患儿,采用随机数字表法分为对照组和治疗组,各42例。对照组予布地奈德福莫特罗粉吸入剂治疗,治疗组在对照组治疗方法的基础上予穴位埋线治疗,2组均连续治疗3个月后统计临床疗效,并比较中医证候评分,肺功能[第1秒用力呼气容积(FEV_(1))、用力肺活量(FVC)、FEV_(1)/FVC比值]、气道炎症因子[嗜酸性粒细胞(EOS)计数、嗜酸性粒细胞阳离子蛋白(ECP)、呼出气一氧化氮(FeNO)]及免疫指标[免疫球蛋白A(IgA)、免疫球蛋白E(IgE)]的变化。结果治疗组总有效率为95.24%(40/42),对照组为80.95%(34/42),2组比较,差异有统计学意义(P<0.05)。治疗前,2组中医证候积分比较,差异无统计学意义(P>0.05),具有可比性;治疗后,2组中医证候积分均显著降低,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组下降更显著(P<0.05)。治疗前,2组FEV_(1)、FVC、FEV_(1)/FVC指标值比较,差异无统计学意义(P>0.05),具有可比性;治疗后,2组上述指标值均升高,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组升高更显著(P<0.05)。治疗前,2组EOS、ECP、FeNO水平比较,差异无统计学意义(P>0.05),具有可比性;治疗后,2组上述指标值均降低,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组降低更显著(P<0.05)。治疗前,2组IgA、IgE水平比较,差异无统计学意义(P>0.05),具有可比性;治疗后,2组IgA水平升高,IgE水平降低,与同组治疗前比较,差异有统计学意义(P<0.05),且治疗组升高或降低更显著(P<0.05)。结论穴位埋线辅助治疗儿童慢性持续期BA肺肾气虚证疗效满意,可显著降低中医证候积分,改善肺功能,抑制气道炎症反应,有效调节机体免疫力,值得临床推广应用。Objective To observe the clinical efficacy of catgut embedding at acupoints as an adjuvant therapy for pediatric bronchial asthma(BA)in the chronic persistent stage of lung-kidney qi deficiency type.MethodsA total of 84 children with BA in the chronic persistent stage of lung-kidney qi deficiency type treated at the Department of Traditional Chinese Medicine,Xuchang Central Hospital,from June 2021 to June2023 were selected and randomly divided into a control group and a treatment group,with 42 cases in each group.The control group was treated with budesonide-formoterol powder inhalation,while the treatment group received catgut embedding at acupoints in addition to the control group's treatment.Both groups were treated continuously for 3 months.Clinical efficacy,TCM syndrome scores,lung function[forced expiratory volume in1 second(FEV_(1)),forced vital capacity(FVC),FEV_(1)/FVC ratio],airway inflammatory factors[eosinophil(EOS)count,eosinophil cationic protein(ECP),fractional exhaled nitric oxide(FeNO)],and immune indicators[immunoglobulin A(IgA),immunoglobulin E(IgE)]were compared before and after treatment.ResultsThe total effective rate in the treatment group was 95.24%(40/42),significantly higher than 80.95%(34/42)in the control group(P<0.05).Before treatment,there were no significant differences in TCM syndrome scores between the two groups(P>0.05),indicating comparability.After treatment,TCM syndrome scores decreased significantly in both groups compared to before treatment(P<0.05),with a more significant decrease in the treatment group(P<0.05).Before treatment,there were no significant differences in FEV_(1),FVC,and FEV_(1)/FVC between the two groups(P>0.05),indicating comparability.After treatment,these indicators increased significantly in both groups(P<0.05),with a more significant increase in the treatment group(P<0.05).Before treatment,there were no significant differences in EOS,ECP,and FeNO levels between the two groups(P>0.05),indicating comparability.After treatment,these indicators decreased sign

关 键 词：儿童 支气管哮喘 慢性持续期 肺肾气虚证 穴位埋线 临床观察 

分 类 号：R256.12[医药卫生—中医内科学]