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作 者:湛楚瑶 张嘉玲 黄秋萍[1] Zhan Chuyao;Zhang Jialing;Huang Qiuping(Guangdong Provincial Hospital of Traditional Chinese Medicine,Guangzhou 510102,Guangdong Province,China)
机构地区:[1]广东省中医院,广东广州510102
出 处:《中外医药研究》2025年第10期28-30,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
摘 要:目的:探讨危重症患者发生ICU获得性衰弱(ICUAW)的危险因素。方法:采用回顾性队列研究方法,收集2023年1月—2024年6月广东省中医院急诊ICU收治的163例危重症患者的临床资料,根据ICUAW诊断标准分为ICUAW组(59例)和非ICUAW组(104例),采用多元Logistic回归模型分析ICUAW的危险因素。结果:ICUAW发生率为36.2%(59/163)。单因素分析显示,ICUAW组患者年龄≥60岁、高血糖、多器官功能衰竭综合征(MODS)、低蛋白血症、机械通气占比均高于非ICUAW组(P<0.05)。Logistic回归分析显示,高血糖、MODS、低蛋白血症和机械通气是危重症患者发生ICUAW的独立危险因素(P<0.05)。结论:高血糖、MODS、低蛋白血症和机械通气是危重症患者发生ICUAW的危险因素。Objective:To investigate the risk factors of ICU acquired weakness(ICUAW)in critically ill patients.Methods:A retrospective cohort study was used to collect the clinical data of one hundred and sixty-three critically ill patients admitted to the emergency ICU of Guangdong Provincial Hospital of Traditional Chinese Medicine from January 2023 to June 2024.According to ICUAW diagnostic criteria,the patients were divided into ICUAW group(59 cases)and non-ICUAW group(104 cases).Multiple Logistic regression model was used to analyze the risk factors of ICUAW.Results:The incidence of ICUAW was 36.2%(59/163).Univariate analysis showed that the proportion of patients aged≥60 years,hyperglycemia,multiple organ failure syndrome(MODS),hypoproteinemia and mechanical ventilation in ICUAW group was higher than that in non-ICUAW group(P<0.05).Logistic regression analysis showed that hyperglycemia,MODS,hypoproteinemia and mechanical ventilation were independent risk factors for ICUAW in critically ill patients(P<0.05).Conclusion:Hyperglycemia,MODS,hypoproteinemia and mechanical ventilation are risk factors for ICUAW in critically ill patients.
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