出 处:《中外医药研究》2025年第10期61-63,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
摘 要:目的:探讨不同的液体加温仪温度在风湿性心脏病(RHD)患者心脏瓣膜置换术中的作用。方法:选取2023年3月—2024年3月在临沂市中心医院确诊的120例RHD患者为研究对象,随机分为研究1组、研究2组、研究3组,每组40例。所有患者接受心脏瓣膜置换术,术中使用体外循环液体加温仪进行保温,温度设置为研究1组38.0℃、研究2组39.0℃和研究3组40.0℃。对比三组患者心脏复跳情况、心肌功能指标水平及术后并发症情况。结果:研究2组、研究3组心脏复跳时间短于研究1组,自动复跳率高于研究1组(P<0.05);研究3组心脏复跳时间短于研究2组,自动复跳率高于研究2组(P<0.05)。麻醉前即刻,三组肌酸激酶同工酶(CK-MB)和心型脂肪酸结合蛋白(H-FABP)水平比较,无统计学差异(P>0.05);体外循环停止即刻、术毕时、术后6 h、术后24 h,三组CK-MB、H-FABP水平高于麻醉前即刻,研究3组CK-MB、H-FABP水平低于研究1组,研究3组H-FABP水平低于研究2组(P<0.05);术后6 h、术后24 h,研究3组CK-MB水平低于研究2组(P<0.05)。三组术后并发症发生率比较,无统计学差异(P>0.05)。结论:在RHD患者心脏瓣膜置换术中,液体加温仪设置为较高温度(40.0℃)时能够缩短心脏复跳时间,提高自动复跳率,保护心肌功能。Objective:To investigate the role of different liquid thermometer temperature in heart valve replacement in patients with rheumatic heart disease(RHD).Methods:A total of one hundred and twenty patients with RHD diagnosed in Linyi Central Hospital from March 2023 to March 2024 were selected as the study objects and randomly divided into study group 1,study group 2 and study group 3,with forty cases in each group.All patients underwent heart valve replacement and were kept warm with a cardiopulmonary bypass fluid heater.The temperature was set to 38.0℃ for study group 1,39.0℃ for study group 2 and 40.0℃ for study group 3.The cardiac recurrence,myocardial function index and postoperative complications were compared among the three groups.Results:The cardioversion time of study group 2 and study group 3 was shorter than that of study group 1,and the automatic cardioversion rate was higher than that of study group 1(P<0.05).The cardioversion time of study group 3 was shorter than that of study group 2,and the automatic cardioversion rate was higher than that of study group 2(P<0.05).Immediately before anesthesia,there were no significant differences in creatine kinase isoenzyme(CK-MB)and cardiac fatty acid-binding protein(HFABP)levels among the three groups(P>0.05).The levels of CK-MB and H-FABP in the three groups were higher than those immediately before anesthesia at the end of cardiopulmonary bypass,after surgery,6 h after surgery and 24 h after surgery.The level of CK-MB and H-FABP in study group 3 was lower than that in study group 1,and the level of H-FABP in study group 3 was lower than that in study group 2(P<0.05).The level of CK-MB in study group 3 was lower than that in study group 2 at 6 h and 24 h after surgery(P<0.05).There was no significant difference in the incidence of postoperative complications among the three groups(P>0.05).Conclusion:During heart valve replacement in patients with RHD,the liquid temperature thermometer can shorten the time of heart relapse,improve the automatic relapse rat
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