规范化用药干预及药学监护在慢性阻塞性肺疾病患者中的应用效果  

Effect of standardized pharmaceutical intervention and pharmaceutical care on clinical efficacy in patients with chronic obstructive pulmonary disease

作　　者：杨旭丹 吴伟 牛建均 杨艳华 曾凡勇 张永红 刘春艳 YANG Xudan;WU Wei;NIU Jianjun;YANG Yanhua;ZENG Fanyong;ZHANG Yonghong;LIU Chunyan(Department of Pharmacy,Dejiang Nation Hospital of Traditional Chinese Medicine,Tongren,Guizhou 565200,China)

机构地区：[1]德江县民族中医院药学部,贵州铜仁565200

出　　处：《医药前沿》2025年第13期50-53,共4页Journal of Frontiers of Medicine

基　　金：贵州省中医药管理局中医药、民族医药科学技术研究课题(QZYY-2023-110)。

摘　　要：目的分析规范化用药干预及药学监护在慢性阻塞性肺疾病(COPD)患者中的应用效果。方法选取2023年1月—2024年1月德江县民族中医院收治的100例COPD患者,采用随机数字表法分为研究组和对照组,每组各50例。对照组采取常规治疗,研究组在对照组基础上给予规范化用药干预及药学监护。比较两组患者的临床疗效、COPD症状评分、用药依从性、肺功能指标、住院时间、不良反应、用药差错及用药种类数。结果干预后,研究组治疗总有效率为96.00%,对照组为88.00%,差异无统计学意义(P>0.05);研究组用药依从性优良率高于对照组(P<0.05);研究组用药种类少于对照组(P<0.05);两组患者不良反应发生率与用药差错率比较差异无统计学意义(P>0.05);研究组住院时间短于对照组(P<0.05)。两组患者COPD疾病症状评估量表评分均低于干预前,且研究组低于对照组(P<0.05);两组患者第1秒用力呼气容积占预计值的百分比高于干预前,且研究组高于对照组(P<0.05)。结论规范化用药干预及药学监护有助于提高COPD患者的治疗效果及用药依从性,可改善COPD患者的症状和肺功能,减少用药种类,缩短住院时间。Objective To investigate the effect of standardized pharmaceutical intervention and pharmaceutical care on clinical efficacy of chronic obstructive pulmonary disease(COPD).Methods A total of 100 patients with COPD treated in Dejiang Nation Hospital of Traditional Chinese Medicine from January 2023 to January 2024 were randomly divided into study group and control group,with 50 cases in each group.The control group received conventional treatment,and the study group received standardized pharmaceutical intervention and pharmaceutical care on the basis of the control group.The clinical efficacy,COPD symptom score,medication compliance,pulmonary function index,length of hospital stay,adverse reactions,medication errors and the number of medication types were compared between the two groups.Results Post-intervention,the overall effective rate of the treatment group was 96.00%,compared to 88.00%in the control group,with no statistically significant difference(P>0.05).The adherence rate in the treatment group was significantly higher than that in the control group(P<0.05).Furthermore,the treatment group utilized fewer types of medication than the control group(P<0.05).There were no statistically significant differences in the incidence of adverse reactions and medication error rates between the two groups(P>0.05).The duration of hospitalization in the treatment group was shorter than that in the control group(P<0.05).Both groups exhibited lower scores on the COPD symptom assessment scale compared to pre-intervention,with the treatment group scoring significantly lower than the control group(P<0.05).Additionally,the percentage of the first-second forced expiratory volume relative to the expected value increased in both groups compared to preintervention,with the treatment group showing a greater improvement than the control group(P<0.05).Conclusions Standardized pharmaceutical intervention and pharmaceutical care is helpful to improve the therapeutic effect and medication compliance of COPD patients,improve the symptoms

关 键 词：慢性阻塞性肺疾病 药学监护 临床观察 治疗效果 服药依从性 

分 类 号：R563[医药卫生—呼吸系统]