血栓弹力图仪和凝血功能六项检测在创伤输血患者中的应用价值  

Application value of thromboelastography and six-item coagulation function test in trauma transfusion patients

作　　者：刘奇 李新颖 亓英婧 LIU Qi;LI Xinying;QI Yingjing(Department of Laboratory Medicine,Laiwu People's Hospital,Ji'nan,Shandong 271100,China)

机构地区：[1]济南市莱芜人民医院检验科,山东济南271100

出　　处：《医药前沿》2025年第13期65-67,71,共4页Journal of Frontiers of Medicine

摘　　要：目的探讨血栓弹力图仪(TEG)和凝血功能六项检测在创伤输血中的应用价值。方法回顾性分析2022年1月—2023年12月济南市莱芜人民医院收治80例创伤输血患者的临床资料,根据检测方法不同分为两组,各40例。对照组输血前接受凝血功能六项检测,观察组输血前接受凝血功能六项检测及TEG检测。分析两组患者纤维蛋白原降解产物(FDP)、凝血酶时间(TT)、活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)、D-二聚体(D-D)、纤维蛋白原水平(FIB),观察组反应时间、凝固时间、angle角、最大凝块强度、纤维溶解指数水平。结果输血后,两组PT、TT、APTT、FDP、D-D水平均降低,且观察组低于对照组,差异有统计学意义(P<0.05);两组FIB水平均升高,且观察组高于对照组,差异有统计学意义(P<0.05)。输血1 d后,观察组反应时间、凝固时间均短于输血前,angle角、最大凝块强度、纤维溶解指数均高于输血前,差异有统计学意义(P<0.05)。结论通过进行TEG检测指导输血,可以有效改善创伤输血患者的凝血功能。Objective To explore the application value of thromboelastography(TEG)and six-item coagulation function test in trauma transfusion patients.Methods A retrospective analysis was conducted on the clinical data of 80 trauma transfusion patients admitted to Laiwu People's Hospital from January 2022 to December 2023.According to different detection methods,the patients were divided into two groups,with 40 cases in each group.The control group received the six-item coagulation function test before transfusion,while the observation group received both the six-item coagulation function test and TEG before transfusion.The levels of fibrinogen degradation products(FDP),thrombin time(TT),activated partial thromboplastin time(APTT),prothrombin time(PT),D-dimer(D-D),fibrinogen(FIB),reaction time,coagulation time,angle,maximum clot strength,and fibrinolysis index were analyzed.Results After transfusion,the levels of FDP,TT,APTT,PT,and D-D in the two groups decreased,and those in the observation group were lower than the control group,with statistically significant differences(P<0.05).The FIB levels of the two groups increased,and the observation group was higher than the control group,with statistically significant differences(P<0.05).One day after transfusion,reaction time and coagulation time in the observation group were shorter than before transfusion,while angle,maximum clot strength,and fibrinolysis index were higher than before transfusion,with statistically significant differences(P<0.05).Conclusions TEG guided transfusioncan effectively improve the coagulation function of trauma transfusion patients.

关 键 词：创伤 输血 凝血功能 血栓弹力图仪 检测分析 

分 类 号：R641[医药卫生—外科学]