安宫牛黄丸治疗致残性脑出血的临床效果  

Effect of Angong Niuhuang pill in the treatment of disabling intracerebral hemorrhage

作　　者：洪文武 谭明明[3] HONG Wenwu;TAN Mingming(Graduate School,Zhejiang Chinese Medical University,Hangzhou,Zhejiang 310000,China;Department of Neurology,Tiantai People's Hospital of Zhejiang Province,Taizhou,Zhejiang 317200,China;Department of Emergency Medicine,Tiantai People's Hospital of Zhejiang Province,Taizhou,Zhejiang 317200,China)

机构地区：[1]浙江中医药大学研究生学院,浙江杭州310000 [2]浙江省天台县人民医院神经内科,浙江台州317200 [3]浙江省天台县人民医院急诊科,浙江台州317200

出　　处：《医药前沿》2025年第13期90-92,95,共4页Journal of Frontiers of Medicine

基　　金：浙江省医学会临床科研基金项目(2021ZYC-A236)。

摘　　要：目的观察安宫牛黄丸治疗致残性脑出血的临床效果。方法选取2023年1—12月浙江省天台县人民医院诊治的致残性脑出血患者100例。按照治疗方式不同分为观察组和对照组,剔除不符合的病例,最终纳入对照组34例,观察组46例。对照组予脑出血常规治疗;观察组在脑出血常规治疗基础上联用安宫牛黄丸。比较两组Barthel指数、美国国立卫生研究院卒中量表(NIHSS)评分、改良Rankin量表(mRS)评分和肝肾功能异常率。结果治疗后14 d,两组NIHSS评分均低于治疗前(P<0.05);治疗后90 d,观察组mRS评分低于治疗前和治疗后14 d,且低于对照组(P<0.05)。治疗前后,两组Barthel指数、肝肾功能异常率比较,差异无统计学意义(P>0.05)。结论安宫牛黄丸辅助治疗致残性脑出血有效性和安全性较好。Objective To observe the clinical efficacy of Angong Niuhuang pill in the treatment of disabling intracerebral hemorrhage.Methods A total of 100 patients with disabling intracerebral hemorrhage treated at Tiantai People's Hospital of Zhejiang Province from January to December 2023 were selected.They were divided into an observation group and a control group based on different treatment methods.After excluding ineligible cases,34 patients were included in the control group and 46 in the observation group.The control group received conventional treatment alone,while the observation group received conventional treatment for intracerebral hemorrhage combined with Angong Niuhuang pill.The Barthel Index,National Institute of Health Stroke Scale(NIHSS)score,modified Rankin Scale(mRS)score,and the incidence of liver and kidney dysfunction were compared between the two groups.Results At 14 days after treatment,the NIHSS scores of the two groups were lower than those before treatment(P<0.05).At 90 days after treatment,the mRS score of the observation group was lower than that before treatment and 14 days after treatment,and lower than that of the control group(P<0.05).There was no statistically significant difference in the Barthel Indexd and the incidence of liver and kidney dysfunction between the two groups before and after treatment(P>0.05).Conclusions Angong Niuhuang pill as an adjunctive therapy for disabling intracerebral hemorrhage demonstrates good efficacy and safety.

关 键 词：安宫牛黄丸 致残性脑出血 改良Rankin量表 BARTHEL指数 美国国立卫生研究院卒中量表 

分 类 号：R286[医药卫生—中药学]