机构地区:[1]益阳师范高等专科学校,湖南益阳413000 [2]益阳市中心医院血管外科,湖南益阳413000
出 处:《现代生物医学进展》2025年第7期1255-1264,共10页Progress in Modern Biomedicine
基 金:益阳市科技计划项目([2022]108号);2024年益阳市银城科技人才托举工程项目(益科联[2024]17号)。
摘 要:目的:运用随机森林模型研究益阳市城乡初中女生对人乳头状瘤病毒(human papilloma virus,HPV)疫苗的认知差异,以为益阳地区HPV疫苗精准推广提供参考。方法:本研究采用分层随机抽样法,于2023年6月至10月招募了益阳地区7所学校(含城市、县城、乡镇三个组别)707位11-14岁初中女生作为调查对象,通过问卷收集该群体HPV疫苗认知情况和HPV疫苗接种意愿及影响因素相关数据。运用SPSS 20.0对收集数据进行差异性分析,运用R-4.3.3的随机森林算法构建模型。结果:三个组别中,城区学校女生的HPV疫苗整体认知水平最高,其次为县城学校。乡镇学校女生听说过HPV、知晓HPV与宫颈癌的关系、了解宫颈癌的危害以及接种HPV疫苗的最佳接种年龄的学生比例均显著低于城区学校(P<0.05)。除县城学校外,城市、乡镇组别整体HPV疫苗接种意愿较高(≥87.91%)。除了接种地点和时间,其他因素在城乡初中女生中未造成显著差异。构建的随机森林模型进一步验证了HPV疫苗认知水平存在城乡差异,疫苗的价格和价数是造成城乡学生接种意愿差异的关键因素。结论:益阳市城乡初中女生对HPV疫苗存在显著认知差异,价格是造成城乡接种意愿差异的首要原因。因此,在制定疫苗推广策略时,应充分考虑目标群体的疫苗认知与价格负担水平,实施城乡差异化的知识传播、健康教育和资金支持措施。Objective:To investigate the cognitive differences in human papilloma virus( HPV)vaccine among urban and rural junior high school girls in Yiyang City by using the random forest model,thereby providing references for the targeted promotion of HPV vaccines.Methods:In this study,a stratified ran dom sampling method was used to recruit 707 junior high school girls aged 11-14 from 7junior high schools( including urban,county town and rural schools) in Yiyang City from June to October 2023.A questionnaire was used to collect data on the HPV vaccine cognition and willingness to receive HPV vaccination,as well as related influencing factors.Data were analyzed using SPSS 20.0,and a random forest algorithm in R-4.3.3 was utilized to construct the model.Results:Among the three groups,urban school girls had the highest level of HPV vaccine cognition,followed by county school girls.The proportion of rural school girls who had heard of HPV,understood the relationship between HPV and cervical cancer,knew the dangers of cervical cancer,and were aware of the optimal age for HPV vaccination was significantly lower than that of urban schools( P<0.05).Except for county schools,the overall willingness to receive HPV vaccination in urban and rural groups was high( ≥ 87.91 %).Except for vaccination location and time,other factors did not significantly differ between urban and rural junior high school girls.The constructed model further confirmed the urban-rural differences in HPV vaccine cognition and found that the price and valency of the vaccine are key factors causing differences in vaccination willingness between urban and rural students.Conclusion:There is a significant cognitive difference in HPV vaccines among urban and rural junior high school girls in Yiyang City,and price is the primary reason for the difference in vaccination willingness between urban and rural areas.Therefore,when formulating vaccine promotion strategies,it is necessary to fully consider the target group's vaccine cognition and the level of price burden
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