膦催化氮杂二烯与马来酰亚胺的1,4-加成反应  

Phosphine-Catalyzed 1,4-Addition of Azadienes with Maleimide

作　　者：何龙 杨金金 罗世纪 马兵 黄训达 HE Long;YANG Jinjin;LUO Shiji;MA Bing;HUANG Xunda(College of Materials Science and Engineering,Guiyang University,Guiyang Guizhou 550005,China)

机构地区：[1]贵阳学院材料科学与工程学院,贵州贵阳550005

出　　处：《辽宁化工》2025年第4期572-574,共3页Liaoning Chemical Industry

基　　金：贵州省贵阳学院大学生创新创业训练项目(项目编号:S2024109760191)。

摘　　要：苯并呋喃骨架广泛存在于天然产物和生物活性分子中,因此,高效获取该类分子骨架的方法近年来受到许多化学工作者的广泛关注。文章主要阐述在三苯基磷的作用下,N-苯基马来酰亚胺与氮杂二烯的1,4-加成反应来构建含有马来酰亚胺结构的苯并呋喃类化合物,对该反应进行了条件筛选,最终以较高的产率得到目标产物。Benzofuran structural motifs commonly found in natural products and bioactive molecules.Therefore,efficient methods to obtain the molecular skeleton of benzofuran have attracted extensive attention in recent years.This paper mainly describes the 1,4-addition reaction of N-phenyl maleimide and azadiene under the action of triphenylphosphorus to construct benzofuran compounds containing maleimide structure.The conditions of the reaction were selected,and the target product was finally obtained with a high yield.

关 键 词：N-苯基马来酰亚胺 氮杂二烯 1 4-加成反应 苯并呋喃 

分 类 号：O625.63[理学—有机化学]