苍耳子黄酮的提取研究  

Study on Extraction of Total Flavonoids from Fructus Xanthii

作　　者：王男[1] 李双宝 李玲 马佳慧 姚佳男 郭天宇 杨磊[1] 王菲[1] WANG Nan;LI Shuangbao;LI Ling;MA Jiahui;YAO Jianan;GUO Tianyu;YANG Lei;WANG Fei(Liaoning Petrochemical University,Fushun Liaoning 113001,China)

机构地区：[1]辽宁石油化工大学,辽宁抚顺113001

出　　处：《辽宁化工》2025年第4期695-699,共5页Liaoning Chemical Industry

基　　金：辽宁省大学生创新创业训练计划项目(项目编号:S202210148053);辽宁省教育厅科学研究一般项目(项目编号:L2020015)。

摘　　要：采用响应面设计法(RSM)优化苍耳子黄酮的提取条件。采用超声波辅助溶剂浸提法对苍耳子黄酮进行提取,通过单因素(超声功率、超声时间、乙醇体积分数、液固比、水浴温度及水浴时间)结合响应面优化实验,得到苍耳子黄酮的最佳提取条件:乙醇体积分数60%,液固比(液体体积(mL)与固体质量(g)的比,下同)为40∶1,超声功率为400 W,超声时间13 min,提取温度60℃,提取时间1.5 h。在此最佳提取条件下,实际得率为85.766 mg·g^(-1),与软件预测数值接近,该模型能较准确地模拟和预测实验得率。Response surface design(RSM)was used to optimize the extraction conditions of flavonoids from Xanthium fructus.The ultrasonic-assisted solvent extraction method was used to extract Xanthium flavonoids.The optimal extraction conditions of Xanthium flavonoids were determined by response surface optimization experiments combined with single factors.The optimum extraction conditions of Xanthium flavonoids were determined as follows:ethanol volume fraction 60%,liquid-to-solid ratio 40∶1,ultrasonic power 400 W,ultrasonic time 13 min,water bath temperature 60℃,and water bath time 1.5 h.Under these conditions,the actual yield was 85.766 mg·g^(-1),which was close to the theoretical predicted value.The model could well simulate and predict the experimental yield.

关 键 词：苍耳子 黄酮 超声波辅助 溶剂浸提法 响应面法 

分 类 号：TQ028.3[化学工程]