磺酸功能化黄原胶催化酰胺烷基萘酚的绿色合成  

GREEN SYNTHESIS OF AMIDOALKYL NAPHTHOLS CATALYZED BY SULFONIC ACID FUNCTIONALIZED XANTHAN

作　　者：李文欢 王英磊[1,2] 田野 曹春 LI Wen-huan;WANG Ying-lei;TIAN Ye;CAO Chun(School of Biological and Chemical Engineering,Nanyang Institute of Technology,Nanyang 473004,China;Henan Key Laboratory of Industrial Microbial Resources and Fermentation Technology,Nanyang 473004,China)

机构地区：[1]南阳理工学院生物与化学工程学院,河南南阳473004 [2]河南省工业微生物资源与发酵技术重点实验室,河南南阳473004

出　　处：《南阳理工学院学报》2025年第2期112-117,共6页Journal of Nanyang Institute of Technology

基　　金：南阳市基础与前沿技术研究计划项目(JCQY007)。

摘　　要：通过黄原胶和氯磺酸的反应,制备了生物质基固体酸磺酸功能化黄原胶。在无溶剂条件下,以磺酸功能化黄原胶为催化剂,芳香醛、2-萘酚和乙酰胺(或苯甲酰胺)在80℃顺利完成“一锅煮”的三组分反应,以84%~96%的产率合成了一系列酰胺烷基萘酚类化合物。该方法的主要优势是反应条件温和,操作简单,磺酸功能化黄原胶安全、环保且可重复使用,满足绿色化学的基本要求。The biomass based solid acid sulfonic acid functionalized xanthan was prepared through the reaction of xanthan and chlorosulfonic acid.Under solvent-free conditions,the one-pot three component reaction of aromatic aldehydes,2-naphthol and acetamide(or benzamide)was successfully completed at 80℃,using sulfonic acid functionalized xanthan as the catalyst.A series of amidoalkyl naphthol compounds were synthesized with yields of 84%~96%.The main merits of this method are mild reaction conditions,simple operation,the sulfonic acid functionalized xanthan is safe,environment-friendly and reusable,which meet the basic requirements of green chemistry.

关 键 词：磺酸功能化黄原胶 酰胺烷基萘酚 多组分反应 绿色合成 回收使用 

分 类 号：O621.3[理学—有机化学]