磁共振相位对比血流定量技术定量股骨头旋股内侧动脉深支的可行靠性研究  

Quantitative flow measurement in evaluating the deep branch of the medial femoral circumflex artery

作　　者：廖振洪 杨洁 刘高元 马春[2] 孙家瑜[1] LIAO Zhenhong;YANG Jie;LIU Gaoyuan;MA Chun;SUN Jiayu(Department of Radiology,West China Hospital,Sichuan University,Chengdu 610041,China;Department of Radiology,Deyang People’s Hospital,Deyang,Sichuan 618000,China)

机构地区：[1]四川大学华西医院放射科,四川成都610041 [2]德阳市人民医院放射科,四川德阳618000

出　　处：《中国实验诊断学》2025年第4期428-433,共6页Chinese Journal of Laboratory Diagnosis

基　　金：四川省医学会资助项目(Q20020)。

摘　　要：目的探讨磁共振相位对比血流定量(quantitative flow,Q-flow)技术在定量股骨头主要供血动脉——旋股内侧动脉深支血流的可靠性。方法前瞻性收集2024年8月至12月间健康志愿者20例(年龄40.7±12.52岁,女性14例),利用3T磁共振与16通道接收线圈对他们的24侧旋股动脉深支进行了Q-flow成像的定量分析。目标动脉行两次Q-flow扫描,以评价重复扫描一致性。一名13年经验的医师和14年经验的技师独立测量Q-flow图中的目标血管,其结果用于评价两测量者间和测量者两次测量的内部的一致性。使用配对样本t/Wilcoxon检验、组内相关系数(intraclass correlation coefficients,ICC)和Bland-Altman分析评估重复扫描测量者间和测量者的内部的一致性。结果在重复扫描、测量者间和测量者内部的分析中,配对样本t/Wilcoxon检验显示差异无统计学意义(P=0.117~0.962);而相关系数分析中,一致性均较好,ICC值为0.85~1。在Bland-Altman分析中,95%一致性阈值以外的点百分比为4.17%~8.33%。结论高分辨率磁共振Q-flow技术能够可靠的定量股骨头主要供血动脉,为评估股骨头血供变化提供了一种有前景的非侵入性技术手段。Objective This study aimed to evaluate the reliability of magnetic resonance phase-contrast quantitative flow(Q-flow)imaging in quantifying blood flow in the deep branch of the medial femoral circumflex artery,the primary arterial supply to the femoral head.Methods A total of 20healthy volunteers(40.7±12.52years,14females)were prospectively recruited between August and December 2024.Quantitative Q-flow imaging analysis of the 24deep branches of the circumflex femoral artery was performed using a 3TMRI scanner with a 16-channel receiver coil.Each target artery underwent two Q-flow scans to evaluate repeat scan consistency.A physician with 13years of experience and a technologist with 14years of experience independently measured the target vessels in the Q-flow images to assess inter-and intra-observer consistency.Paired sample t/Wilcoxon tests,intraclass correlation coefficients(ICC),and Bland-Altman analysis were used to evaluate repeat scan consistency,inter-observer consistency,and intra-observer consistency.Results In the repeat scan,inter-observer,and intra-observer analyses,the paired sample t/Wilcoxon tests showed no significant differences(P=0.117~0.962).The correlation analysis indicated good consistency,with ICC values ranging from 0.85to 1.In the Bland-Altman analysis,the percentage of points outside the 95%limits of agreement ranged from 4.17%to 8.33%.Conclusion High-resolution magnetic resonance Q-flow imaging demonstrates good reliability in quantifying blood flow in the primary arteries supplying the femoral head.This technique offers a promising noninvasive approach to assessing changes in femoral head perfusion.

关 键 词：相位对比磁共振成像 股骨头 血供 可靠性 定量分析 

分 类 号：R445.2[医药卫生—影像医学与核医学]