黄芩药理作用及其常用配伍药对研究进展  

Research Progress on Pharmacological Effects of Scutellaria baicalensis and Its Commonly Used Compatible Drug Pairs

作　　者：范灏奎 李彪 邹润 曾元宁 匡海学[1] 王秋红[1,2] FAN Haokui;LI Biao;ZOU Run;ZENG Yuanning;KUANG Haixue;WANG Qiuhong(School of Pharmacy,Heilongjiang University of Chinese Medicine,Harbin 150040,China;School of Traditional Chinese Medicine,Guangdong Pharmaceutical University,Guangzhou 510006,China)

机构地区：[1]黑龙江中医药大学药学院,黑龙江哈尔滨150040 [2]广东药科大学中药学院,广东广州510006

出　　处：《现代中药研究与实践》2025年第1期91-96,共6页Research and Practice on Chinese Medicines

基　　金：国家重点研发计划项目(2018YFC1707100);广东省重点领域研发计划(2020B111112002);国家中医药管理局中医药传承与创新“百千万”人才工程-岐黄工程首席科学家支持项目(国中医药人教函[2021]7号);国家中医药管理局中医药传承与创新“百千万”人才工程(岐黄工程)岐黄学者支持项目(国中医药人教函[2018]284号);2022年全国名老中医药专家传承工作室建设项目(国中医药人教函[2022]75号);第七批全国老中医药专家学术经验继承工作项目(国中医药人教函[2022]76号);黑龙江省“头雁”团队支持项目(黑龙江省头雁行动领导小组文件[2019]5号)。

摘　　要：黄芩是一种被广泛使用的传统草药,具有抗炎、抗肿瘤、抗菌和抗氧化等药理活性,临床上可有效治疗多种疾病。黄芩主要活性成分有黄芩苷、黄芩素、汉黄芩苷和汉黄芩素等。临床上黄芩常与黄连、柴胡、知母、大黄等中药配伍应用。通过对黄芩的药理作用机制以及常见黄芩药对的临床应用与药理作用进行综述,为将来更好地开发黄芩及其药对提供参考。Scutellaria baicalensis is a widely used traditional herbal medicine with rich pharmacological activities,including anti-inflammatory,anti-tumor,anti-bacterial and anti-oxidant activities,which are clinically effective in the treatment of a wide range of diseases.This herbal medicine mainly consists of active substances,such as baicalin,baicalein,wogonoside and wogonin,et al.Clinically,Scutellaria baicalensis is often used in combination with Coptis chinensis Franch.,Bupleurum chinense DC.,Anemarrhena asphodeloides Bge.,Rheum officinale Baill.and other traditional Chinese medicines.The pharmacological effects and mechanisms of Scutellaria baicalensis as well as the clinical applications of common Scutellaria baicalensis medicinal pairs are summarized to provide a reference for the better development of Scutellaria baicalensis and its medicinal pairs in the future.

关 键 词：黄芩 药对 药理作用 配伍理论 

分 类 号：R285.5[医药卫生—中药学]