黄连温胆汤治疗失眠的研究进展  

The research progress of Huanglian Wendan Decoction to treat insomnia

作　　者：蔡瑞 邢耀军 Cai Rui;Xing Yaojun(Shanghai Pudong New District Liuzao Community Health Service Center,Shanghai 201322,China)

机构地区：[1]上海市浦东新区六灶社区卫生服务中心,上海201322

出　　处：《首都食品与医药》2025年第8期19-22,共4页Capital Food Medicine

摘　　要：失眠,一种机体主观上对于其睡眠时间或质量感到不满意的临床疾病,患者通常表现为夜间难以入睡、睡后易醒、多梦、日间疲倦等。长期失眠严重影响患者的生活质量,目前其西医治疗常用镇静催眠药,如苯二氮䓬类、西泮类等,长期使用可能存在成瘾性、神经功能受损等不良反应。失眠在中医理论中属“不寐”“卧不安”等范畴,黄连温胆汤为治疗痰热扰心型失眠患者的常用方剂,近年来研究该方对于失眠的临床及基础试验逐渐增多。对于黄连温胆汤治疗失眠的研究进行综述发现,黄连温胆汤治疗失眠的作用机制包括神经内分泌通路、炎症介质通路、代谢组学途径等方面。A clinical disease that is not satisfied with the sleep time or quality of insomnia is a subjective manner.Patients usually show that it is difficult to fall asleep at night,wake up after sleeping,dreams,and fatigue during the day.Long-term insomnia seriously affects the quality of life of patients.At present,its commonly used sedative hypnotic pills,such as benzodiazo,and western categories.Long-term use may have adverse reactions such as addiction and damage to nerve function.Insomnia is“not sleeping”and“lying”,etc.Huanglian Wendan Decoction also has a common prescription for the treatment of phlegm-heat-disturbing heart insomnia patients.In recent years,it has studied the number of clinical and basic experiments on insomnia.A review of the study of Huanglian Wendan Decoction for insomnia and found that the mechanism of the role of Huanglian Wendan Decoction for insomnia includes neurological endocrine pathway,inflammatory media channels,and metabolic group learning pathways.

关 键 词：失眠 研究进展 黄连温胆汤 临床研究 

分 类 号：R256.23[医药卫生—中医内科学]