儿童围术期输血研究进展  

Research progress in pediatric perioperative blood transfusion

作　　者：廖晨曦 廖刃[1] LIAO Chenxi;LIAO Ren(Department of Anesthesiology,West China Hospital,Sichuan University,Chengdu 610041,China)

机构地区：[1]四川大学华西医院麻醉科,四川成都610041

出　　处：《中国输血杂志》2025年第4期572-577,共6页Chinese Journal of Blood Transfusion

摘　　要：儿童围术期输血管理具有显著的特殊性,因其生理差异和输血相关并发症风险,需采取个性化的输血策略和优化的管理方法。本文综述了近年来儿童围术期输血的研究进展,重点探讨了儿童输血的特点、主要并发症及其防控策略,包括限制性和个性化输血、抗纤溶药物应用、血液制品的选择与处理等。此外,文章还总结了大数据、人工智能和多中心临床试验在儿童输血管理中的应用前景,并提出了制定儿童专用输血指南和推动血液替代品研发的重要性。未来,通过精准输血和多学科合作,儿童围术期输血的安全性和有效性将进一步提高,为改善围术期预后提供有力支持。Pediatric perioperative blood transfusion management requires individualized transfusion strategies and optimized management approaches due to children′s physiological differences and higher risk of transfusion-related complications.This review discusses recent advancements in pediatric perioperative transfusion,focusing on unique characteristics,major complications,and preventive strategies,including restrictive and individualized transfusion approaches,antifibrinolytic medications,and optimal blood product selection and processing.Additionally,the paper highlights the potential role of big data,artificial intelligence,and multi-center clinical trials in advancing pediatric transfusion management and emphasizes the need for pediatric-specific transfusion guidelines and the development of blood substitutes.Moving forward,precise transfusion strategies and interdisciplinary collaboration will further enhance the safety and efficacy of pediatric perioperative transfusion,improving perioperative outcomes.

关 键 词：儿童围术期输血 个体化输血策略 并发症 大数据 人工智能 血液替代品 

分 类 号：R457.1[医药卫生—治疗学]