精杞养阴方合枣苓安神方治疗阴虚质兼失眠的临床疗效观察  

Observation on the therapeutic effect of Jingqi Yangyin Formula combined with Zaoling Anshen Formula on yin deficiency and insomnia

作　　者：刘晶晶[1] 杨欣怡 彭鑫 张春梅[1] 唐丽燕[1] 张毅[1] 周天玉[1] LIU Jingjing;YANG XINyi;PENG Xin(Sichuan Academy of Chinese Medicine Sciences,Chengdu 610041,China)

机构地区：[1]四川省中医药科学院,四川成都610041

出　　处：《四川中医》2025年第3期199-202,共4页Journal of Sichuan of Traditional Chinese Medicine

基　　金：第七批全国老中医专家学术经验传承项目(编号:PCPYRSC2023-CQSC2)。

摘　　要：目的:观察精杞养阴方合枣苓安神方治疗阴虚质兼失眠的临床疗效。方法:采用随机对照的临床研究,筛选90例阴虚质兼失眠的患者作为研究对象,随机分为体质组、睡眠组、体质睡眠组,每组各30例,分别使用精杞养阴方、枣苓安神方、精杞养阴方合枣苓安神方,疗程30天,对比三组治疗后的总有效率、匹兹堡睡眠质量指数(PSQI)、阴虚质转化分及血常规、肝肾功等安全性指标。结果:治疗后体质睡眠组总有效率80.00%,睡眠组总有效率63.33%,体质组总有效率56.67%,体质睡眠组总有效率优于体质组,差异有统计学意义(P<0.05);治疗后三个组的PSQI总评分较治疗前均明显降低,差异有统计学意义(P<0.05),三组组间比较差异无统计学意义(P>0.05);对三组组间PSQI各成分评分分析比较,体质睡眠组在改善睡眠质量、入睡时间及日间功能障碍方面优于体质组,差异有统计学意义(P<0.05);三组治疗后阴虚质转化分均下降,差异有统计学意义(P<0.05);PSQI评分与阴虚质转化分呈正相关,相关性显著有统计学意义(P<0.01);治疗前后受试者血常规、肝肾功、血脂等差异无统计学差异(P>0.05)。结论:精芪养阴方合枣苓安神方对阴虚质兼失眠患者临床疗效较好,优于精芪养阴方或枣苓安神方,既有利于调理阴虚体质,同时有助于帮助睡眠,安全性好,值得临床推广。Objective: To observe the clinical efficacy of Jingqi Yangyin Formula combined with Zaoling Anshen Formula in treating yin deficiency and insomnia. Methods: A randomized controlled clinical study was conducted to select 90patients with yin deficiency and insomnia as the research object. They were randomly divided into a physique group,a sleep group,and a physique sleep group,with 30patients in each group. They were treated with Jingqi Yangyin Recipe,Zaoling Anshen Recipe,and Jingqi Yangyin Recipe combined with Zaoling Anshen Recipe for 30days. The total effective rate,Pittsburgh Sleep Quality Index (PSQI),Yin Deficiency Substance Transformation Score,blood routine,liver and kidney function and other safety indicators of the three groups after treatment were compared. Results: After treatment,the total effective rate of the physical sleep group was 80%,the sleep group was 63.33%,and the physical group was 56.67%. The total effective rate of the physical sleep group was better than that of the physical group,with a statistically significant difference ( P <0.05). After treatment,the total PSQI scores of the three groups were significantly reduced compared to before treatment,with a statistically significant difference ( P <0.05),there was no statistically significant difference between the three groups ( P >0.05). Analysis and comparison of PSQI scores among the three groups showed that the constitutional sleep group was superior to the sleep group in improving sleep quality,falling asleep time,and daytime dysfunction,with statistically significant differences ( P <0.05). After treatment,the conversion score of yin deficiency in all three groups decreased,and the difference was statistically significant ( P <0.05). The PSQI score is positively correlated with the Yin deficiency transformation score,and the correlation is statistically significant ( P <0.01). Before and after treatment,there was no statistically significant difference in blood routine,liver and kidney function,and blood lipid values among the subjec

关 键 词：阴虚质 失眠 疗效观察 

分 类 号：R255[医药卫生—中医内科学]