瑞马唑仑全麻诱导对妇科子宫全切术患者循环稳定性的影响  

Effect of General Anesthesia Induction on Circulatory Stability in Patients Undergoing Gynaecological Total Hysterectomy

作　　者：薛凯凯 冯翔 焦育娟[1] XUE Kaikai;FENG Xiang;JIAO Yujuan(Department of Anesthesiology,First Hospital of Shanxi Medical University,Taiyuan 030001,Shanxi,China)

机构地区：[1]山西医科大学第一医院麻醉科,山西太原030001

出　　处：《系统医学》2025年第7期84-86,98,共4页Systems Medicine

摘　　要：目的 探讨妇科子宫全切术采用瑞马唑仑全麻诱导对于机体循环的稳定性的影响。方法 非随机选取山西医科大学第一医院于2022年5月—2023年2月收治的80例妇科子宫全切术患者为研究对象,根据麻醉方式的不同分为观察组及常规组,每组40例。观察组采用瑞马唑仑全麻诱导,常规组采用丙泊酚诱导,对比两组不同时间点平均动脉压、心率、血氧饱和度变化及术后麻醉复苏情况、不良反应发生情况。结果 T1~T3时刻,平均动脉压、心率及血氧饱和度的波动幅度比较,常规组高于观察组,差异均有统计学意义(P均<0.05)。观察组患者术后定向力恢复时间(17.24±0.25)h、自主呼吸恢复时间(5.27±0.55)h、术毕苏醒时间(5.63±0.72)h及言语应答时间(7.24±0.61)均短于常规组的(23.23±0.27)h、(8.24±0.61)h、(7.61±0.52)h、(11.27±0.55)h,差异均有统计学意义(t=102.955,22.870,14.100,31.032;P均<0.05)。且两组不良反应发生率比较,观察组为5.00%(2/40),常规组为20.00%(8/40),观察组低于常规组,差异有统计学意义(χ^(2)=4.114,P<0.05)。结论 瑞马唑仑全麻诱导妇科子宫全切术可维持患者内循环稳定,提高麻醉诱导安全性。[Objective]To investigate the effect of general anesthesia induction with remazolam on the stability of circulation in gynecological hysterectomy.Methods A total of eighty patients with gynecological hysterectomy admitted to the First Hospital of Shanxi Medical University from May 2022 to February 2023 were non-randomly selected as the research objects.According to the different anesthesia methods,they were divided into observation group and routine group,with forty cases in each group.The observation group was induced by remifentanil general anesthesia,and the routine group was induced by propofol.The changes of mean arterial pressure,heart rate,blood oxygen saturation at different time points,postoperative anesthesia recovery and adverse reactions were compared between the two groups.Results At T1-T3,the fluctuation range of mean arterial pressure,heart rate and blood oxygen saturation in the routine group was higher than that in the observation group,and the differences were statistically significant(all P<0.05).The post⁃operative orientation recovery time(17.24±0.25)h,spontaneous breathing recovery time(5.27±0.55)h,postoperative recovery time(5.63±0.72)h and speech response time(7.24±0.61)in the observation group were shorter than(23.23±0.27)h,(8.24±0.61)h,(7.61±0.52)h,(11.27±0.55)h in the routine group,the differences were statistically significant(t=102.955,22.870,14.100,31.032;all P<0.05).The incidence of adverse reactions in the observation group was 5.00%(2/40),and that in the routine group was 20.00%(8/40).The incidence of adverse reactions in the observation group was lower than that in the routine group,and the difference was statistically significant(χ^(2)=4.114,P<0.05).Conclusion Remazolam general anesthesia induction of gynecological hysterectomy can maintain the stability of inter⁃nal circulation and improve the safety of anesthesia induction.

关 键 词：瑞马唑仑 妇科 子宫全切术 麻醉诱导 稳定性 

分 类 号：R614.2[医药卫生—麻醉学]