替硝唑联合盐酸左氧氟沙星治疗慢性盆腔炎的临床有效性  

Clinical Effectiveness of Tenidazole Plus Levofloxacin Hydrochloride in Treating Chronic Pelvic Inflammation

作　　者：王小燕 王秋燕 WANG Xiaoyan;WANG Qiuyan(Department of Obstetrics and Gynecology,Jinan Women and Children's Hospital,Jinan 250001,Shandong,China)

机构地区：[1]济南妇儿医院妇产科,山东济南250001

出　　处：《系统医学》2025年第7期150-152,共3页Systems Medicine

摘　　要：目的 评估替硝唑联合盐酸左氧氟沙星治疗慢性盆腔炎的临床效果。方法 回顾性选取2022年6月—2023年4月济南妇儿医院收治的100例慢性盆腔炎患者的临床资料,按照治疗方法不同分为两组,参照组(n=50)采用替硝唑治疗,研究组(n=50)采用盐酸左氧氟沙星联合替硝唑治疗。比较两组患者治疗效果,下腹坠痛改善时间与不良反应发生率。结果 研究组治疗总有效率为100.00%(50/50),明显高于参照组的84.00%(42/50),差异有统计学意义(χ^(2)=6.658,P<0.05)。研究组患者下腹坠痛改善时间(8.37±0.12)d,较参照组的(11.73±1.29)d更短,差异有统计学意义(t=18.338,P<0.05)。研究组患者腹泻、胃肠不适、小腹痛的发生率低于参照组,差异有统计学意义(P<0.05)。结论 替硝唑与盐酸左氧氟沙星联用可可提高慢性盆腔炎治疗效果,加速症状改善,且安全性更优。Objective To evaluate the clinical effect of tinidazole combined with levofloxacin hydrochloride in the treatment of chronic pelvic inflammatory disease.Methods The clinical data of 100 patients with chronic pelvic in⁃flammatory disease admitted to Jinan Women and Children's Hospital from June 2022 to April 2023 were retrospec⁃tively selected and divided into two groups according to different treatment methods.The reference group(n=50)was treated with tinidazole,and the study group(n=50)was treated with levofloxacin hydrochloride combined with tinida⁃zole.The treatment effect,the improvement time of lower abdominal pain and the incidence of adverse reactions were compared between the two groups.Results The total effective rate of the study group was 100.00%(50/50),which was significantly higher than 84.00%(42/50)of the reference group,the difference was statistically significant(χ^(2)=6.658,P<0.05).The improvement time of lower abdominal pain in the study group(8.37±0.12)d was shorter than that in the reference group(11.73±1.29)d,and the difference was statistically significant(t=18.338,P<0.05).The incidence of di⁃arrhea,gastrointestinal discomfort and abdominal pain in the study group was lower than that in the reference group,and the difference was statistically significant(P<0.05).Conclusion The combination of tinidazole and levofloxacin hydrochloride can improve the therapeutic effect of chronic pelvic inflammatory disease,accelerate the improvement of symptoms,and have better safety.

关 键 词：替硝唑 盐酸左氧氟沙星 慢性盆腔炎 治疗有效性 

分 类 号：R711[医药卫生—妇产科学]