海军官兵幽门螺杆菌检测阳性率影响因素分析  

Analysis of factors influencing the helicobacter pylori detection positive rate in naval personnel

作　　者：朱惠云 董潇阳 周显祝 吴浩 黄文 李兆申 杜奕奇 Zhu Huiyun;Dong Xiaoyang;Zhou Xianzhu;Wu Hao;Huang Wen;Li Zhaoshen;Du Yiqi(Department of Gastroenterology,The First Affiliated Hospital of Naval Medical University,Shanghai 200433,China;National Clinical Research Center for Digestive Diseases,Shanghai 200433,China)

机构地区：[1]海军军医大学第一附属医院消化内科,上海200433 [2]国家消化系统疾病临床医学研究中心,上海200433

出　　处：《中华航海医学与高气压医学杂志》2025年第3期243-248,共6页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

摘　　要：目的分析海军官兵幽门螺杆菌(Hp)检测阳性率及其影响因素。方法2022年9月至2023年12月便利抽取4377名海军部队官兵作为研究对象,采用^(13)C呼气试验进行Hp检测,通过调查问卷采集官兵基本情况和近3个月消化系统症状发作情况,分析海军官兵Hp检测阳性率的影响因素。结果4377名海军官兵总体Hp检测阳性率为31.7%。Hp检测阳性率与性别、吸烟、近3个月累计出任务时长、进食酸奶、2周内使用抗生素、3个月内伴有腹痛及3个月内伴有恶心相关,差异均有统计学意义(均P<0.05)。多因素Logistic回归显示,年龄38~47岁(OR=0.628,P=0.011)、2周内使用抗生素(OR=0.655,P=0.027)是Hp检测阳性的独立保护因素,男性(OR=1.857,P=0.009)、近3个月累计出任务时长31~60 d(OR=1.321,P=0.020)、有吸烟史(OR=1.210,P=0.005)是Hp检测阳性的独立危险因素。结论针对Hp检测阳性率的影响因素,需加强官兵的Hp感染健康教育和卫生宣教工作,完善基层部队卫生设施,纠正不良生活习惯,高度警惕腹痛、恶心等症状,系统制订官兵Hp预防、检测、根除方案,为提高官兵战斗力提供保障。Objective To analyze the Helicobacter pylori(Hp)positivity rate and its related influencing factors among naval personnel.Methods From September 2022 to December 2023,4377 naval personnel were selected as the study population by the convenience sampling method.The ^(13)C-urea breath test was employed for detecting Hp infection.Basic demographic information and the occurrence of gastrointestinal symptoms in the past three months were collected through questionnaire surveys for analyzing the factors influencing the Hp positivity rate among naval personnel.Results The overall Hp positivity rate among the 4377 naval personnel was 31.7%.The positivity rate was significantly related with gender,smoking,cumulative mission duration in the past three months,yogurt consumption,antibiotic use in the past two weeks,abdominal pain in the past three months,and nausea in the past three months(all P<0.05).Multivariate logistic regression analysis revealed that age(38-47 years)(OR=0.628,P=0.011)and antibiotics use in the past two weeks(OR=0.655,P=0.027)were independent protective factors against Hp positivity,while being male(OR=1.857,P=0.009),cumulative mission duration in the past three months(31-60 days)(OR=1.321,P=0.020),and smoking(OR=1.210,P=0.005)were independent risk factors for Hp positivity.Conclusion Regarding the factors influencing Hp positivity,it is necessary to enhance health education and hygiene promotion concerning Hp infection among naval personnel,improve sanitation facilities at the small-unit level,correct unhealthy lifestyle habits,and maintain a high vigilance for symptoms such as abdominal pain and nausea.A systematic plan for the prevention,detection,and eradication of Hp among naval personnel should be developed to ensure their combat readiness.

关 键 词：幽门螺杆菌 海军 阳性率 影响因素 

分 类 号：R82[医药卫生—临床医学]