湿润烧伤膏联合地奥司明治疗肛周脓肿患者的效果  

Effects of Moist exposed burn ointment combined with Diosmin in treatment of patients with perianal abscess

作　　者：郭松杨 朱粟意 吴雪华 GUO Songyang;ZHU Suyi;WU Xuehua(Anorectal Department of Luohe Hospital of Traditional Chinese Medicine,Luohe 462000 Henan,China)

机构地区：[1]漯河市中医院肛肠科,河南漯河462000

出　　处：《中国民康医学》2025年第9期117-120,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:观察湿润烧伤膏联合地奥司明治疗肛周脓肿术后患者的效果。方法:选取2019年5月至2023年5月该院收治的60例肛周脓肿患者进行前瞻性研究,按照随机数字表法将其分为研究组与对照组各30例。两组均采用三间隙引流手术治疗,术后对照组采用地奥司明片治疗,研究组在对照组基础上联合湿润烧伤膏治疗,比较两组临床疗效,术后炎性因子[肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)]水平、手术前后肛门功能指标(最大肛管收缩压、肛管静息压、Wexner肛门功能评估量表)水平、术后创面恢复指标(创面面积、创面水肿、创面渗液、肉芽组织生长)水平,以及术后并发症发生率。结果:研究组治疗总有效率为93.33%,高于对照组的73.33%,差异有统计学意义(P<0.05);术后3 d,两组IL-6、TNF-α水平均低于术后1 d,且研究组低于对照组,差异有统计学意义(P<0.05);术后7 d,两组Wexner评分、最大肛管收缩压、肛管静息压水平均低于术前,且研究组低于对照组,差异有统计学意义(P<0.05);术后7 d,两组创面面积、创面水肿、创面渗液评分均低于术后1 d,且研究组低于对照组,两组肉芽组织生长评分均高于术后1 d,且研究组高于对照组,差异有统计学意义(P<0.05);两组术后并发症发生率比较,差异无统计学意义(P>0.05)。结论:湿润烧伤膏联合地奥司明治疗肛周脓肿患者可提高治疗总有效率,改善创面恢复指标水平,降低炎性因子和肛门功能指标水平的效果优于单纯地奥司明治疗。Objective:To observe effects of Moist exposed burn ointment combined with Diosmin in treatment of patients with perianal abscess.Methods:A prospective study was conducted on 60 patients with perianal abscess admitted to the hospital from May 2019 to May 2023.According to the random number table method,they were divided into study group and control group,30 cases in each group.Both groups were treated with three-cavity clearance surgery.The control group was treated with Diosmin tablets after the surgery,while the study group was treated with Moist exposed burn ointment on the basis of that of the control group.The clinical efficacy,the levels of postoperative inflammatory factors[tumor necrosis factor-α(TNF-α),interleukin-6(IL-6)]and anal function indexes(maximum anal canal systolic pressure,anal canal resting pressure,Wexner anal function assessment scale),the postoperative wound recovery indexes(wound area,wound edema,wound exudate,granulation tissue growth)levels before and after the surgery,and the incidence of postoperative complications were compared between the two groups.Results:The total effective rate of treatment in the study group was 93.33%,which was higher than 73.33%in the control group,and the difference was statistically significant(P<0.05).Three days after the surgery,the levels of IL-6 and TNF-αin the two groups were lower than those 1 day after the surgery,those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Seven days after the surgery,the Wexner scores and the levels of maximum anal canal systolic pressure and anal canal resting pressure in the two groups were lower than those before the surgery,those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).Seven days after the surgery,the scores of wound area,wound edema and wound exudate in the two groups were lower than those 1 day after the surgery,and those in the study group were lower than those

关 键 词：湿润烧伤膏 肛周脓肿 创面 肛门功能 炎性因子 

分 类 号：R657.1[医药卫生—外科学]