硒对动物机体细胞损伤的保护作用研究进展  

Progress on studying the effects of selenium on protecting the cellular damage in animals

作　　者：王圣学 范颖 王振敏 屈蓓蓓 禹小芳 蒋竹英 WANG Shengxue;FAN Ying;WANG Zhenmin;QU Beibei;YU Xiaofang;JIANG Zhuying(Yongzhou Bureau of Agricultural and Rural Affairs of Hunan Province,Yongzhou 425000,China)

机构地区：[1]永州市农业农村局,湖南永州425000

出　　处：《养殖与饲料》2025年第5期10-14,共5页Animals Breeding and Feed

摘　　要：[目的]研究硒对动物机体细胞损伤的保护作用机制,为硒在动物生产中应用提供参考依据。[方法]综述硒的多种生理功能,探讨在细胞受损伤的情况下硒对家禽缓解氧化应激、提高机体免疫、拮抗毒性元素等的影响。[结果]硒具有抗氧化应激、提高机体免疫、拮抗毒性元素等作用,可以作为良好的抗生素替代品来提升家禽的生产性能、免疫性能和抗氧化性能,改善家禽的肠道健康。[结论]硒可以作为动物生产中有效解毒剂、保护剂。目前针对硒调节动物机体细胞损伤的研究在家畜上的研究相对较少,对于信号通路之间协同、关联调控作用机制少有报道,还有待进一步研究。[Objectives]The protective mechanism of selenium against cellular damage in animals at the cellular level was reviewed to provide reference for the application of selenium in animal production.[Methods]The multiple physiological functions of selenium were summarized.The effects of selenium on alleviating oxidative stress,enhancing immune function,and antagonizing toxic elements in livestock and poultry under cellular damage were discussed.[Results]Selenium has the effects of antioxidant stress,enhancing immune function,and antagonizing toxic elements.It can be used as a good alternative to antibiotics to improve the production performance,immune function,antioxidant capacity,and the intestinal health of poultry.[Conclusions]Selenium can be used as an effective antidote and protector in animal production.Current studies on selenium regulation of cellular damage in animals are relatively less focused on livestock,and there are few reports on the synergistic and correlated regulatory mechanisms between signaling pathways and other signaling pathways,which require further in-depth study.

关 键 词：硒 细胞损伤 保护作用 微量营养元素 营养性饲料添加剂 

分 类 号：S816.7[农业科学—饲料科学]