中医特色护理方案对终末期糖尿病肾病血液透析患者胃肠道症状的影响  

Impacts of TCM-featured Nursing Program on Gastrointestinal Symptoms in Patients with End-stage Diabetic Nephropathy Undergoing Hemodialysis

作　　者：葛慧莉 徐慧 GE Huili;XU Hui(Rugao Hospital of Traditional Chinese Medicine,Rugao 226500,China)

机构地区：[1]如皋市中医院,江苏如皋226500

出　　处：《西部中医药》2025年第4期123-126,共4页Western Journal of Traditional Chinese Medicine

基　　金：南通市中医医疗联盟项目(TZYK202215)。

摘　　要：目的:分析中医特色护理方案对终末期糖尿病肾病(end stage diabetic nephropathy,ESDN)血液透析患者胃肠道症状的影响。方法:选取60例终末期ESDN血液透析患者,均于血液透析期间存在不同类型的胃肠道症状,根据随机数字表法分为对照组(30例,接受常规护理)和观察组(30例,在对照组的基础上接受中医特色护理方案),两组均干预2个月。比较两组肠道微生态、胃肠道症状、生活质量、血糖、肾功能水平。结果:干预2个月后,观察组厚壁菌门占比高于对照组(P<0.05),拟杆菌门、变形菌门、放线菌门占比低于对照组(P<0.05);观察组腹痛、消化不良、便秘、腹泻、进食困难、反流评分低于对照组(P<0.05);观察组空腹血糖、餐后2 h血糖、24 h尿蛋白排泄率、尿素氮水平低于对照组(P<0.05);观察组生活质量好、生活质量一般者比率高于对照组(P<0.05)。结论:给予ESDN血液透析患者中医特色护理方案,可改善其胃肠道菌群分布,缓解胃肠道不适症状,调节血糖水平及肾功能状态,进而促进生活质量的提高。Objective:To explore the influences of traditional Chinese medicine(TCM)-characterized nursing program on gastrointestinal symptoms in patients with end-stage diabetic nephropathy(ESDN)undergoing hemodialysis.Methods:Sixty ESDN patients undergoing hemodialysis were chosen,having different types of gastrointestinal symptoms during hemodialysis,and allocated to the control group(30 cases,receiving conventional care),and the observation group(30 cases,accepting TCM-characterized nursing program based on the control group),and both groups accepted two months of the intervention.To compare intestinal microecology,gastrointestinal symptoms,quality of life,and the levels of blood glucose and renal function between the two groups.Results:After two months of the intervention,the observation group was higher than the control group in the proportion of Firmicutes(P<0.05),lower than the control group in the proportions of Bacteroidetes,Proteobacteria,and Actinobacteria(P<0.05);the scores of abdominal pain,dyspepsia,constipation,diarrhea,feeding disorder and regurgitation(P<0.05);the observation group was lower than the control group in fasting bloodglucose,2 h postprandial plasma glucose(2 h PG),and the 24 h urine protein(24 h UP)excretion and the levels of usea nitrogen(P<0.05);the observation group was higher than the control group in the ratios of good and average quality of life(P<0.05).Conclusion:TCM-characterized nursing administered to ESDN patients undergoing hemodialysis could improve the distribution of gastrointestinal flora,mitigate gastrointestinal discomforts,adjust the levels of blood glucose and renal function,so as to improve quality of life.

关 键 词：糖尿病肾病 中医特色护理 肠道微生态 血液透析 

分 类 号：R255.4[医药卫生—中医内科学]