鼓胀退水贴对肝硬化腹水患者门静脉血流动力学及生活质量的影响  

Influence of Tympanites Ascites-eliminating Plaster on Quality of Life and Portal Vein Hemodynamics in Patients with Cirrhotic Ascites

作　　者：傅琪琳 黄甫 李粉萍 唐颖慧 王亚娟 王红 薛敬东 FU Qilin;HUANG Fu;LI Fenping;TANG Yinghui;WANG Yajuan;WANG Hong;XUE Jingdong(Shaanxi Provincial TCM Hospital,Xi'an 710002,China)

机构地区：[1]陕西省中医医院,陕西西安710002

出　　处：《西部中医药》2025年第4期131-134,共4页Western Journal of Traditional Chinese Medicine

基　　金：陕西省自然科学基础研究计划(2019JQ-981)。

摘　　要：目的:观察鼓胀退水贴对肝硬化腹水患者门静脉血流动力学和生活质量的影响。方法:将100例肝硬化腹水患者按照就诊顺序分成观察组和对照组,每组50例。两组均给予常规保肝、利尿治疗,观察组在常规治疗基础上,给予鼓胀退水贴外敷,共治疗3周。观察两组腹水消退情况、门静脉血流动力学变化及生活质量评分变化。结果:总有效率观察组[86%(43/50)]高于对照组[74%(37/50)](P<0.05)。治疗后两组患者门静脉内径差异无统计学意义(P>0.05),而两组患者门静脉血流速度、门静脉血流量均较治疗前降低(P<0.05),且观察组均低于对照组(P<0.05)。治疗后两组患者生理功能、生理职能、总体健康、活力、情感职能、精神健康评分均高于治疗前(P<0.05),且观察组生理功能、总体健康、活力、精神健康评分均明显高于对照组(P<0.05)。结论:鼓胀退水贴可加速腹水消退,能在一定程度上改善患者生活质量,而其治疗肝硬化腹水的机制可能在于控制门静脉血流速度,减少门静脉血流灌注,从而降低门静脉压力。Objective:To explore the influence of tympanites ascites-eliminating plaster on portal vein hemodynamics and quality of life in patients with cirrhotic ascites.Methods:All 100 patients were randomized into the observation group and the control group with 50 cases in each group.Both groups accepted conventional liver protection and diuretic therapy,the observation group accepted external application of tympanites asciteseliminating plaster on the foundation of conventional treatment,for three weeks.To observe the elimination conditions of ascites,portal vein hemodynamics and the scores of quality of life between both groups.Results:Total effective rate of the observation group was[86%(43/50)],higher than[74%(37/50)]of the control group(P<0.05).The difference had no statistical meaning in portal vein diameter between the two groups after the treatment(P>0.05),while portal venous blood flow velocity and portal venous blood flow were lower than before the treatment(P<0.05),and the observation group was lower than the control group(P<0.05).After the treatment,the scores of physiologic function,physiological role,overall health status,vigor,emotional role and mental health of the two groups were higher than before the treatment(P<0.05),and the scores of physiologic function,overall health status,vigor and mental health of the observation group were obviously higher than these of the control group(P<0.05).Conclusion:Tympanites ascites-eliminating plaster could accelerate the elimination of ascites,improve the patients'quality of life to a certain extent,and the mechanism of treating cirrhotic ascites might be related to controlling portal venous blood flow velocity and reducing portal venous blood flow perfusion,thereby reducing portal vein pressure.

关 键 词：肝硬化 腹水 鼓胀退水贴 穴位贴敷 门静脉 生活质量 

分 类 号：R256.42[医药卫生—中医内科学]