基于meta分析探究中医体质与高血压的关系  

Exploring therelationship between traditional Chinese medicine constitution types and hypertension:a meta-analysis

作　　者：朱启豪 谭甲莲 李建容 易珍奎 ZHU Qihao;TAN Jialian;LI Jianrong(Jiangsu Provincial Hospital of Traditional Chinese Medicine Chongqing Branch(Yongchuan Hospital of Traditional Chinese Medicine),Yongchuan 402160,China)

机构地区：[1]江苏省中医院重庆医院(重庆市永川区中医院),重庆永川402160

出　　处：《四川中医》2025年第4期208-213,共6页Journal of Sichuan of Traditional Chinese Medicine

基　　金：中医体质与高血压病及抗高血压药物基因的相关性研究(编号:2022yc-jckx20002)。

摘　　要：目的:探究中医体质与高血压的相关性,为高血压的中医药防治提供循证依据。方法:利用国内外数据库进行文献检索,时间从建库至2024年9月15日,纳入文献使用EndNoteX7进行管理,重要信息提取后记录在Excel表格,采用纽卡斯尔-渥太华量表对文献进行质量评价,Meta分析使用Stata17软件进行。结果:最终纳入文献16篇,共计9312人。分析结果显示痰湿质OR=1.96[95%CI(1.47,2.61)]、阴虚质OR=1.84[95%CI(1.61,2.11)]、血瘀质OR=1.70[95%CI(1.05,2.73)]以及气虚质OR=1.36[95%CI(1.16,1.58)]的人群发生高血压风险更高,而平和质OR=0.53[95%CI(0.37,0.75)]人群发生高血压的风险更低。结论:痰湿质、阴虚质、血瘀质、气虚质是高血压易感体质,对高血压易感体质人群可开展中医药调节,达到“治未病”的重要意义。Objective:To explore the correlation between traditional Chinese medicine(TCM)constitution types and hyper-tension,providing evidence-based support for the prevention and treatment of hypertension using TCM.Methods:A literature search was conducted using domestic and international databases,covering the period from database inception to July 15,2024.The included literature was managed with EndNote X7,and key information was recorded in Excel.The Newcastle-Ottawa Scale was used for quality assessment of the studies,and Meta-analysis was performed using Stata 17software.Results:A total of 16studies involving 9,312participants were included.The analysis revealed that individuals with Phlegm-Dampness Constitution(OR=1.96[95%CI(1.47,2.61)]),Yin Deficiency Constitution(OR=1.84[95%CI(1.61,2.11)]),Blood Sta-sis Constitution(OR=1.70[95%CI(1.05,2.73)]),and Qi Deficiency Constitution(OR=1.36[95%CI(1.16,1.58)])had a higher risk of developing hypertension.Conversely,individuals with a Balanced Constitution(OR=0.53[95%CI(0.37,0.75)])had a lower risk of hypertension.Conclusion:Phlegm-Dampness,Yin Deficiency,Blood Stasis,and Qi Deficiency constitutions are associated with increased susceptibility to hypertension.For people with these predisposing constitutions,traditional Chinese medicine can be used for regulation,achieving the significant importance of“preventive treat-ment”.

关 键 词：中医体质 高血压 个体化诊疗 早期干预 META分析 

分 类 号：R259[医药卫生—中西医结合]