发热伴血小板减少综合征合并恙虫病混合感染1例  

A SINGLE CASE OF COINFECTION WITH SEVERE FEVER WITH THROMBOCYTOPENIA SYNDROME AND SCRUB TYPHUS IN DALIAN,CHINA

作　　者：吴克亚 孔令艳 邢俊[2] 庞为[2] 周祎[2] 梁玉红[2] 金圣浩 齐上[2] WU Ke-ya;KONG Ling-yan;XING Jun;PANG Wei;ZHOU Yi;LIANG Yu-hong;JIN Sheng-hao;QI Shang(The First Affiliated Hospital of Dalian Medical University,Dalian 116011,Liaoning,China;Dalian Center for Disease Control and Prevention,Dalian 116035,Liaoning,China)

机构地区：[1]大连医科大学附属第一医院,辽宁大连116011 [2]大连市疾病预防控制中心,辽宁大连116035

出　　处：《寄生虫与医学昆虫学报》2025年第1期48-51,共4页Acta Parasitologica et Medica Entomologica Sinica

摘　　要：本文报告了大连市首例发热伴血小板减少综合征合并恙虫病混合感染病例。患者因反复发热7 d、意识不清1 d入院,经病原微生物宏基因组测序(mNGS)、SFTSV定量PCR及酶联免疫吸附(ELISA)IgM实验检测,结果显示恙虫病东方体和SFTSV核酸阳性,结合临床表现和流行病学史,确诊为混合感染。This article reports a first case of combined infection with severe fever with thrombocytopenia syndrome(SFTS)and scrub typhus in Dalian City.The patient was admitted to the hospital due to recurrent fever for 7 days and loss of consciousness for 1 day.Pathogen metagenomic sequencing(mNGS),SFTSV quantitative PCR,and enzyme-linked immunosorbent assay(ELISA)IgM tests were performed,showing positive results for Orientia tsutsugamushi and SFTSV nucleic acids.Based on clinical manifestations and epidemiological history,the patient was diagnosed with combined infections.

关 键 词：混合感染 发热伴血小板减少综合征 恙虫病 

分 类 号：R512.8[医药卫生—内科学]