新生儿头线圈在颅脑MRI检查中的应用研究  

Study of application on neonatal head coil in brain MRI examination

作　　者：任庆发 巩贺 殷志杰[1] 王静[1] 刘泉源[1] 徐东昊 杨浩然 荣康 李祥林[2] REN Qingfa;GONG He;YIN Zhijie;WANG Jing;LIU Quanyuan;XU Donghao;YANG Haoran;RONG Kang;LI Xianglin(Department of Radiology,Binzhou Medical University Hospital,Binzhou 256600,China;School of Medical Imaging,Binzhou Medical University,Yantai 264003,China;Department of Radiology,Central Hospital of Shengli Oil Field,Dongying 257100,China;Department of Radiology,Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250014,China)

机构地区：[1]滨州医学院附属医院放射科,滨州256600 [2]滨州医学院医学影像学院,烟台264003 [3]胜利油田中心医院放射科,东营257100 [4]山东中医药大学附属医院放射科,济南250014

出　　处：《磁共振成像》2025年第4期99-104,共6页Chinese Journal of Magnetic Resonance Imaging

基　　金：国家自然科学基金项目(编号:62176181);山东省重点研发计划项目(编号:2018YFJH0501)。

摘　　要：目的探讨16通道新生儿头线圈用于新生儿颅脑磁共振成像(magnetic resonance imaging,MRI)的临床价值。材料与方法应用体模检测法,选择质子密度加权成像(proton density weighted imaging,PDWI)序列,设置相同参数,分别对新生儿头线圈及成人头线圈进行体外实验,处理图像得到两线圈的信噪比(signal-to-noise ratio,SNR)进行客观定量分析。前瞻性收集2022年8月至2023年12月进行颅脑MRI检查的44例健康新生儿,以简单随机法分为2组,应用新生儿头线圈和成人头线圈以相同参数对两组新生儿均采集加速因子R=2时的T2WI序列图像,测试图像SNR和灰白质对比噪声比(contrast-to-noise ratio,CNR);再分别调整加速因子R=2、3、4、5、6,测试线圈的并行采集能力。综合分析新生儿颅脑图像,计算两线圈的图像SNR和灰白质CNR,并由两名影像学诊断医师独立评价两线圈的并行采集能力,利用t检验对图像SNR和灰白质CNR主观评分进行统计分析。结果体外实验中,新生儿头线圈的SNR高于成人头线圈,平均为成人头线圈的1.4倍,部分皮层表层区超过2倍。临床实验中,新生儿头线圈在双侧丘脑、基底神经节和额叶区域的图像SNR高于成人头线圈;新生儿头线圈在双侧丘脑、基底神经节与额叶白质的灰白质CNR高于成人头线圈,差异均具有统计学意义(P<0.001)。调整加速因子后,新生儿头线圈显示具有较高的并行采集能力。结论新生儿头线圈有利于改善新生儿颅脑的MRI图像质量。Objective:To investigate the clinical value of 16-channel neonatal head coil for neonatal cranial magnetic resonance imaging(MRI).Materials and Methods:Using the water film detection method,proton density weighted imaging(PDWI) sequence was selected,and the same parameters were set.The neonatal head coil and adult head coil were respectively tested in vitro.The signal-to-noise ratio(SNR) of the two coils was obtained by processing the images for objective quantitative analysis.A total of 44healthy neonates undergoing brain magnetic resonance examination from August 2022 to December 2023 were prospectively collected and divided into 2 groups by simple random method.To test image SNR and contrast-to-noise ratio(CNR) of gray and white matter.The T2WI sequence images with acceleration factor R = 2 were collected for both groups using neonatal head coil and adult head coil with the same parameters.Then the acceleration factor R = 2,3,4,5,6 was adjusted respectively to test the parallel acquisition capability of the coil.Neonatal brain images were comprehensively analyzed,image SNR and gray and white matter CNR of the two coils were calculated,and the parallel acquisition ability of the two coils was independently evaluated by two imaging diagnostic physicians,and the subjective score of image SNR and gray and white matter CNR was statistically analyzed by t-test.Results:In vitro experiment,the SNR of neonatal head coil was 1.4 times higher than that of adult head coil,and some cortical surface areas were more than 2 times.In clinical experiments,the SNR of neonatal head coil in bilateral thalamus,basal ganglia and frontal lobe region were higher than those of adult head coil,the CNR of gray matter in bilateral thalamus and basal ganglia and white matter in frontal lobe of neonatal head coil is higher than that of adult head coil,and the differences was statistically significant(P < 0.001).After adjusting the acceleration factor,the neonatal head coil showed high parallel acquisition capability.Conclusions:Neonatal hea

关 键 词：新生儿头线圈 信噪比 对比噪声比 磁共振成像 并行采集 

分 类 号：R445.2[医药卫生—影像医学与核医学] R722.19[医药卫生—诊断学]