体素内不相干运动在心肌微循环中的应用进展  

Research progress on the application of intravoxel incoherent motion in myocardial microcirculation

作　　者：赵磊 徐宁 王翠艳[2] ZHAO Lei;XU Ning;WANG Cuiyan(Department of Imaging,Jinan Zhangqiu District People's Hospital,Jinan 250200,China;Department of Imaging,Shandong Provincial Hospital Affiliated to Shandong First Medical University,Jinan 250021,China)

机构地区：[1]济南市章丘区人民医院影像科,济南250200 [2]山东第一医科大学附属山东省立医院影像科,济南250021

出　　处：《磁共振成像》2025年第4期174-179,共6页Chinese Journal of Magnetic Resonance Imaging

摘　　要：心肌微循环功能障碍作为心力衰竭、心源性猝死等不良事件的独立危险因素,其早期定量评估成为心血管影像领域的研究热点。体素内不相干运动(intravoxel incoherent movement,IVIM)作为一种可评估组织微循环功能的磁共振成像技术,为心肌微循环功能障碍的早期诊断提供了无创、多参数、可动态化评估的全新视角。因此,本文系统阐述IVIM技术在心肌微循环功能评估中的可重复性与稳定性,探讨IVIM技术在不同病理状态下的心肌微循环量化特征,并指出了目前IVIM技术在心肌微循环功能评估中尚未完全解决的问题与新的探讨方向,可使后来研究者能够更全面地掌握最新动向。Myocardial microcirculatory dysfunction serves as an independent risk factor for adverse cardiovascular events such as heart failure and cardiogenic sudden death.Early quantitative assessment of myocardial microcirculation has therefore become a research hotspot in cardiovascular imaging.Intravoxel incoherent movement(IVIM) magnetic resonance imaging,a technique capable of evaluating tissue microcirculatory function,provides a non-invasive,multi-parametric,and dynamically assessable novel perspective for early diagnosis of myocardial microcirculatory dysfunction.This paper systematically elaborates on the repeatability and stability of IVIM in myocardial microcirculation assessment,explores the quantitative characteristics of myocardial microcirculation under different pathological conditions using IVIM,and highlights the unresolved issues and emerging research directions in current IVIM-based myocardial microcirculation evaluations.This comprehensive review aims to enable subsequent researchers to grasp the latest developments in this field.

关 键 词：高血压心肌病 缺血性心肌病 肥厚型心肌病 体素内不相干运动 磁共振成像 心肌微循环 

分 类 号：R445.2[医药卫生—影像医学与核医学] R541.7[医药卫生—诊断学]