心脏磁共振在评估蒽环类化疗药物对乳腺癌患者心肌损伤的研究进展  

Cardiac magnetic resonance in evaluating cardioxicity induced by anthracycline chemotherapy in breast cancer

作　　者：陈双燕 付兵[2] 苏春艳 杨智[2] CHEN Shuangyan;FU Bing;SU Chunyan;YANG Zhi(College of Medicine and Life Sciences,Chengdu University of Traditional Chinese Medicine,Chengdu 611130,China;Department of Radiology,Chengdu Fifth People's Hospital,Chengdu 611130,China)

机构地区：[1]成都中医药大学医学与生命科学学院,成都611130 [2]成都市第五人民医院放射科,成都611130

出　　处：《磁共振成像》2025年第4期180-185,共6页Chinese Journal of Magnetic Resonance Imaging

基　　金：四川省卫生健康委员会科研课题(编号:20PJ216)。

摘　　要：乳腺癌是中国女性最常见的恶性肿瘤。蒽环类药物作为乳腺癌患者的主要化疗药物,能有效控制肿瘤进展,改善患者远期预后。但是蒽环类化疗药物存在一定的心肌毒性,在肿瘤化疗过程中伴随着不同程度的心肌损伤,影响患者生存质量。因此,早期检测出蒽环类药物所致心肌损伤,有助于临床早期干预,保护患者心脏功能。心脏磁共振(cardiac magnetic resonance,CMR)凭借其无辐射、无创、多参数、多序列的成像优势,在早期检测心肌受损方面存在潜在价值。本文就CMR在评估接受蒽环类药物治疗的乳腺癌患者所致心肌毒性方面的价值做一综述,以便提高影像科及临床医生对此类患者心肌损伤的认识,并促进CMR在评估乳腺癌化疗所致心肌损伤的应用。Breast cancer is the most common malignancy in Chinese women.As the commonest chemotherapy drugs for breast cancer,anthracyclines can effectively control tumor progression and improve the long-term prognosis of patients.However,anthracyclines have some cardiotoxicity and are associated with various degrees of myocardial damage during tumor chemotherapy,affecting patients'quality of life.Therefore,early detection of myocardial damage caused by anthracyclines is helpful for early clinical intervention and protection of patients'heart function.Cardiac magnetic resonance(CMR)has potential value in early detection of myocardial damage due to its non-radiative,non-invasive,multi-parameter,multi-sequence imaging advantages.This review reviews the value of CMR in assessing cardiotoxicity in breast cancer patients treated with anthracyclines,in order to enhance the awareness of radiologist and clinicians regarding myocardial injury in such patients and improve the appliaction of CMR in the assement of myocardial injury caused by chemotherapy for breast cancer.

关 键 词：乳腺癌 心脏磁共振 蒽环类药物 心肌毒性 化疗 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]