影像组学在中晚期宫颈癌综合治疗中的应用进展  

Progress in the application of radiomics in the comprehensive treatment of advanced cervical cancer

作　　者：熊灵玲 华丽[1] 陈绍俊[1] XIONG LingLing;HUA Li;CHEN ShaoJun(Department of Oncology,the Fourth Affiliated Hospital of Guangxi Medical University,Liuzhou 545005,China;Guangxi Medical University,Nanning 530021,China)

机构地区：[1]广西医科大学第四附属医院肿瘤科,柳州545005 [2]广西医科大学,南宁530021

出　　处：《磁共振成像》2025年第4期208-213,共6页Chinese Journal of Magnetic Resonance Imaging

基　　金：广西重点研发计划项目(编号:桂科AB21196014)。

摘　　要：宫颈癌起病隐匿,发现时大多处于中晚期。中晚期宫颈癌的综合治疗模式主要包括手术和放疗相关的两大类,但目前指南对于中晚期宫颈癌术前或根治性放化疗前联合新辅助化疗(neoadjuvant chemotherapy,NACT),以及术后或根治性放化疗后使用辅助化疗(adjuvant chemotherapy,ACT)这两大类常用治疗模式的适宜人群及有无生存获益都存在争议,缺乏明确的共识推荐。影像组学能从不同模态的影像中提取高通量影像特征,定量评估肿瘤病变,有利于对获益人群的筛选及对疗效和生存的评估,有可能可以为中晚期宫颈癌综合模式的个体化治疗提供临床决策依据。本文对影像组学在中晚期宫颈癌手术和放疗相关综合治疗模式的应用进行综述,以期为中晚期宫颈癌的综合治疗提供新的思路和策略。Cervical cancer starts insidiously and is mostly found in the advanced stage.The comprehensive treatment modes of advanced cervical cancer mainly include two categories related to surgery and radiotherapy.However,current guidelines remain controversial regarding the appropriate patient population and survival benefits of commonly used treatment strategies,such as neoadjuvant chemotherapy(NACT) before surgery or radical chemoradiotherapy and adjuvant chemotherapy(ACT) after surgery or radical chemoradiotherapy,and lack of clear consensus recommendations.Radiomics can extract high-throughput imaging features from different imaging modalities,quantitatively assess tumor lesions,aid in identifying beneficiary populations and evaluating treatment efficacy and survival outcomes.It may provide a clinical decision-making basis for the individualized treatment of comprehensive models in advanced cervical cancer.This article reviews the application of radiomics in the comprehensive treatment models associated with surgery and radiotherapy for advanced cervical cancer,aiming to offer new ideas and strategies for its comprehensive treatment.

关 键 词：中晚期宫颈癌 新辅助化疗 手术 同期放化疗 辅助化疗 磁共振成像 影像组学 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.33[医药卫生—诊断学]