姜皮中三个新化合物的分离与鉴定  

Isolation and identification of three new compounds from Zingiber officinale(Ginger) peel

作　　者：牛惠莹 方鸿斌 司盈盈 郑玉忠[2] 王彦志[1] NIU Hui-ying;FANG Hong-bin;SI Ying-ying;ZHENG Yu-zhong;WANG Yan-zhi(School of Pharmacy,Henan University of Chinese Medicine,Zhengzhou 450046,China;School of Food Engineering and Biotechnology,Guangdong Provincial Key Laboratory of Functional Substances in Medicinal Edible Resources and Healthcare Products,Hanshan Normal University,Chaozhou 521041,China)

机构地区：[1]河南中医药大学药学院,河南郑州450046 [2]韩山师范学院食品工程与生物技术学院,广东省粤东药食资源功能物质与治未病研究重点实验室,广东潮州521041

出　　处：《药学学报》2025年第4期1046-1051,共6页Acta Pharmaceutica Sinica

基　　金：国家中医药管理局中药化学高水平重点学科;广东省粤东药食资源功能物质与治未病研究重点实验室(2021B1212040015)。

摘　　要：运用MCI Gel CHP-20、Sephadex LH-20和ODS等柱色谱结合半制备高效液相色谱等方法,从姜皮正丁醇部位中分离得到3个新化合物。结合1D-NMR、2D-NMR、HR-ESI-MS、圆二色谱(CD)和计算CD (ECD)等方法鉴定其结构分别为dendranthemoside C (1)、zingpyranoside E (2)、zingpyranoside F (3)。Three new compounds were isolated from the n-butanol fraction of Zingiber officinale(Ginger)peel by MCI Gel CHP-20,Sephadex LH-20,ODS and semipreparative high performance liquid chromatography.Their structures were identified as dendranthemoside C(1),zingpyranoside E(2),zingpyranoside F(3) by 1D-NMR,2D-NMR,HR-ESI-MS,circular dichroism(CD) and ECD calculation techniques.

关 键 词：姜皮 化学成分 倍半萜 二苯庚烷苷 分离鉴定 

分 类 号：R284[医药卫生—中药学]