鼓室注射地塞米松治疗突发性耳聋的临床效果  

Clinical Efficacy of Intratympanic Injection of Dexamethasone in the Treatment of Sudden Hearing Loss

作　　者：雷关民 陈春霞[1] 朱俊茹 LEI Guanmin;CHEN Chunxia;ZHU Junru(Department of Otolaryngology,The Second People's Hospital of Anyang,Anyang Henan 455000,China;Department of Otolaryngology,Anyang Maternal and Child Health Hospital,Anyang Henan 455000,China)

机构地区：[1]安阳市第二人民医院耳鼻咽喉科,河南安阳455000 [2]安阳市妇幼保健院耳鼻咽喉科,河南安阳455000

出　　处：《临床研究》2025年第5期45-48,共4页Clinical Research

摘　　要：目的探讨突发性耳聋(SHL)患者采用鼓室注射地塞米松治疗的临床效果,为临床提供参考。方法选取2020年1月至2023年9月在安阳市第二人民医院接受治疗的60例SHL患者,按照随机数字表法分为对照组(n=30)和研究组(n=30)。对照组患者给予常规治疗方案,研究组患者给予鼓室注射地塞米松治疗。对两组患者临床疗效、临床症状评分、纯音听阈值、不良反应发生情况进行比较。结果研究组患者治疗有效率高于对照组,差异有统计学意义(P<0.05);治疗后,两组患者耳鸣、耳闷、眩晕的评分均降低,且研究组低于对照组,差异有统计学意义(P<0.05);治疗后,两组患者0.5 kHz、1.0 kHz、2.0 kHz纯音听阈值均降低,且研究组低于对照组,差异有统计学意义(P<0.05);研究组患者不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论鼓室注射地塞米松应用于SHL患者治疗中,能够提高临床疗效,改善临床症状、纯音听阈值,减少不良反应发生率。Objective To investigate the clinical efficacy of intratympanic injection of dexamethasone in patients with sudden hearing loss(SHL)and provide a reference for clinical practice.Methods Sixty SHL patients treated at The Second People's Hospital of Anyang from January 2020 to September 2023 were selected and randomly divided into a control group(n=30)and a study group(n=30).The control group received conventional treatment,while the study group received intratympanic injection of dexamethasone.The clinical efficacy,clinical symptom scores,pure tone thresholds,and incidence of adverse reactions were compared between the two groups.Results The study group had a higher effective treatment rate compared to the control group,with statistically significant differences(P<0.05).After treatment,scores for tinnitus,ear fullness,and vertigo decreased in both groups,with the study group showing lower scores than the control group,indicating statistically significant differences(P<0.05).Post-treatment pure tone thresholds at 0.5 kHz,1.0 kHz,and 2.0 kHz decreased in both groups,with the study group exhibiting lower thresholds than the control group,demonstrating statistically significant differences(P<0.05).The incidence of adverse reactions in the study group was lower than that in the control group,with statistically significant differences(P<0.05).Conclusion The application of intratympanic injection of dexamethasone in SHL treatment can improve clinical efficacy,enhance clinical symptoms,lower pure tone thresholds,and reduce the incidence of adverse reactions.

关 键 词：鼓室注射 地塞米松 突发性耳聋 临床效果 

分 类 号：R764.43[医药卫生—耳鼻咽喉科]