对比剂剂量与肾小球滤过率比值预测CI-AKI发生的研究进展  

Value of contrast agent dose to glomerular filtration rate ratio in predicting contrast-induced acute kidney injury

作　　者：买尔孜亚·吾斯曼 王顺[1] Maierziya·Wusiman;Wang Shun(The First Affiliated Hospital of Xinjiang Medical University,Urumqi,Xinjiang 830011,China)

机构地区：[1]新疆医科大学第一附属医院,新疆乌鲁木齐830011

出　　处：《首都食品与医药》2025年第10期20-22,共3页Capital Food Medicine

基　　金：“天山英才”医药卫生高层次人才培养计划(编号:TSYC202301B012)。

摘　　要：肾小球滤过率(GFR)可用于评估对比剂诱导的急性肾损伤(CI-AKI)的风险,既可以单独使用,也可以作为对比剂剂量与GFR比值的一部分。该比值已被证实可用于评估冠状动脉造影和经皮冠状动脉介入治疗后CI-AKI的风险,但尚未在计算机断层扫描中应用。相对GFR和绝对GFR均可用于评估CI-AKI风险,但因缺乏明确的区分,可能会造成混淆并成为潜在的错误来源。当给予对比剂且剂量与CI-AKI相关时,应采用绝对GFR替代常用的相对GFR,克-碘(g-I)与绝对GFR比值可能是评估CI-AKI风险的最佳指标。Glomerular filtration rate(GFR)can be used to assess the risk of contrast induced acute kidney injury(CI-AKI),either alone or as part of the ratio of contrast dose to GFR.This ratio has been shown to be useful for assessing the risk of CI-AKI after coronary angiography and percutaneous coronary intervention,but has not been used in computed tomography.Both relative and absolute GFR can be used to assess the risk of CI-AKI,but the lack of a clear distinction can be confusing and a potential source of error.Absolute GFR should be used instead of the commonly used relative GFR when a contrast agent is administered and the dose is associated with CI-AKI,and the ratio of gram-iodine(g-I)to absolute GFR may be the best indicator for assessing the risk of CI-AKI.

关 键 词：对比剂 肾小球滤过率 急性肾损伤 

分 类 号：R692[医药卫生—泌尿科学]