2008—2023年云南省曲靖市人间布鲁氏菌病流行病学特征及临床诊断情况分析  

Epidemiological characteristics and clinical diagnosis of human brucellosis in Qujing City,Yunnan Province from 2008 to 2023

作　　者：杨富萍 徐守先 于彬彬[1] 赵溯[1] 张青[1] 杨秋菊[1] 杨娇 杨向东[1] Yang Fuping;Xu Shouxian;Yu Binbin;Zhao Su;Zhang Qing;Yang Qiuju;Yang Jiao;Yang Xiangdong(Yunnan Provincial Key Laboratory of Natural Focal Disease Control and Prevention Technology,Yunnan Provincial Institute of Endemic Disease Control and Prevention,Dali 671000,China;Department of Endemic Disease Prevention and Control,Disease Prevention and Control Center of Qujing City,Qujing 655000,China)

机构地区：[1]云南省地方病防治所、云南省自然疫源性疾病防控技术重点实验室,大理671000 [2]曲靖市疾病预防控制中心地方病防治科,曲靖655000

出　　处：《中华地方病学杂志》2025年第4期318-322,共5页Chinese Journal of Endemiology

摘　　要：目的掌握云南省曲靖市人间布鲁氏菌病(简称布病)流行病学特征及临床诊断情况。方法通过中国疾病预防控制信息系统传染病报告信息管理系统,回顾性收集2008年1月至2023年12月曲靖市报告的布病病例的基本情况和临床诊断资料。采用描述性流行病学方法,对布病的流行概况,三间分布(时间、人群、地区)特征及诊断情况进行分析。结果2008—2023年曲靖市共报告布病病例1417例,无死亡病例。布病年均发病率为1.49/10万,2009、2010年均无病例报告,2023年发病率最高(7.82/10万),布病发病率呈现逐年上升趋势(χ^(2)_(趋势)=1874.58,P<0.001)。6—11月病例数占61.54%(872/1417)。布病病例以36~65岁年龄组为主,占67.82%(961/1417);其中,男性954例、女性463例,男女性别比为2.06∶1.00;职业以农民为主,占84.33%(1195/1417)。布病病例主要分布在陆良县(621例)、宣威市(282例)和师宗县(137例),占73.39%(1040/1417)。病例发病至确诊时间间隔中位数为13 d,间隔时间≤7、8~30、≥31 d的病例分别占32.11%(455/1417)、40.16%(569/1417)、27.73%(393/1417)。63.94%(906/1417)的病例在曲靖市辖区内医疗机构确诊。结论曲靖市布病发病率呈现逐年上升趋势,男性、中老年、农民为主要发病人群,夏季和秋季为发病高峰期,陆良县、宣威市和师宗县为高发地区。大部分病例发病至确诊时间间隔在30 d以内,且可在本辖区内医疗机构确诊。ObjectiveTo study the epidemiological characteristics and clinical diagnosis of human brucellosis in Qujing City,Yunnan Province.MethodsThrough the Infectious Disease Reporting Information Management System of the China Disease Prevention and Control Information System,the basic information and clinical diagnostic data of brucellosis cases reported in Qujing City from January 2008 to December 2023 were retrospectively collected.Descriptive epidemiological methods were used to analyze the epidemic profile,three distribution characteristics(time,population,region),and diagnosis of brucellosis.ResultsA total of 1417 brucellosis cases were reported in Qujing City from 2008 to 2023,with no death.The annual average incidence of brucellosis was 1.49/100000,with no cases reported in 2009 and 2010,and the highest incidence in 2023(7.82/100000).The incidence of brucellosis showed an increasing trend year by year(χ^(2)_( trend)=1874.58,P<0.001).The number of cases from June to November accounted for 61.54%(872/1417).The majority of brucellosis cases were in the age group of 36-65 years old,accounting for 67.82%(961/1417).Among them,there were 954 males and 463 females,with a gender ratio of 2.06∶1.00.Farmers were the main occupation,accounting for 84.33%(1195/1417).The cases were mainly distributed in Luliang County(621 cases),Xuanwei City(282 cases)and Shizong County(137 cases),accounting for 73.39%(1040/1417).The median interval between onset and diagnosis was 13 days,and the cases with intervals≤7 d,8-30 d,and≥31 d accounted for 32.11%(455/1417),40.16%(569/1417),and 27.73%(393/1417),respectively.Totally 63.94%(906/1417)of the cases were confirmed in medical institutions in Qujing City.ConclusionsThe incidence of brucellosis in Qujing City is increasing year by year,with men,middle-aged and elderly people and farmers as the main population,summer and autumn as the peak period,and Luliang County,Xuanwei City and Shizong County as the high incidence areas.Most cases have an interval of less than 30 days between onset

关 键 词：布鲁氏菌病 流行病学特征 临床诊断 

分 类 号：R516.7[医药卫生—内科学]